Overview

  • Product name
    Anti-FCRL2 antibody
    See all FCRL2 primary antibodies
  • Description
    Chicken polyclonal to FCRL2
  • Host species
    Chicken
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (Human) -corresponds to N terminal amino acids 1-135 of FCRL2.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgY
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab37365 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Predicted molecular weight: 56 kDa.

Target

  • Function
    May have an regulatory role in normal and neoplastic B cell development.
  • Tissue specificity
    Expressed in the secondary lymphoid organs, spleen and lymph node. Expression is limited to the mature B-cell lines. Highly expressed in CD19 and within the mantle zones of the tonsil tissue. Isoform 2 is expressed in the spleen, peripheral blood and bone marrow. Isoform 2 and isoform 4 are expressed in B-cell lines. Preferentially expressed in memory B-cells (at protein level).
  • Sequence similarities
    Contains 4 Ig-like C2-type (immunoglobulin-like) domains.
  • Domain
    Contains 2 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). The phosphorylated ITIM motif bind the SH2 domain of PTPN6.
  • Post-translational
    modifications
    Isoform 2 is N- and O-glycosylated, and phosphorylated.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
    • Alternative names
      • CD307b antibody
      • Fc receptor homolog 2 antibody
      • Fc receptor like protein 2 antibody
      • Fc receptor-like protein 2 antibody
      • FcR-like protein 2 antibody
      • FcRH2 antibody
      • FCRL 2 antibody
      • FcRL2 antibody
      • FCRL2_HUMAN antibody
      • IFGP family protein 4 antibody
      • IFGP4 antibody
      • Immunoglobulin receptor translocation associated 4 protein antibody
      • Immunoglobulin receptor translocation-associated protein 4 antibody
      • IRTA4 antibody
      • SH2 domain containing phosphatase anchor protein 1 antibody
      • SH2 domain-containing phosphatase anchor protein 1 antibody
      • SPAP1 antibody
      see all

    References

    ab37365 has not yet been referenced specifically in any publications.

    Publishing research using ab37365? Please let us know so that we can cite the reference in this datasheet.

    Customer reviews and Q&As

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    1 Review or Q&A

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    Votes: Highest First

    The customer kindly phoned to discuss anti-Fc R antibodies.

    Thank you for contacting Abcam.

    The product which we spoke about on the phone today is actually against the Fc region of human IgG and not against any of the Fc Receptor proteins which you inquiring about. While we do not have a single produ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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