Overview

  • Product name
    Anti-FCRL4 antibody
  • Description
    Rabbit polyclonal to FCRL4
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cat, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 35-84 (FKGERVTLTC NGFQFYATEK TTWYHRHYWG EKLTLTPGNT LEVRESGLYR) of Human IRTA1 (NP_112572).

  • Positive control
    • 293T cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab98279 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 57 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    May function as an inhibitor of the B-cell receptor signaling. May function in the B-cell-mediated immune response.
  • Tissue specificity
    Specifically expressed by memory and monocytoid B-cells which populate spleen and lymph nodes. Preferentially expressed in memory B-cells associated with mucosal tissue (at protein level).
  • Involvement in disease
    Note=A chromosomal aberration involving FCRL4 is found in non-Hodgkin lymphoma (NHG). Translocation t(1;1)(p36.3; q21.1-2).
    Note=A chromosomal aberration involving FCRL4 is found in multiple myeloma (MM). Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein.
  • Sequence similarities
    Contains 4 Ig-like C2-type (immunoglobulin-like) domains.
  • Post-translational
    modifications
    Phosphorylated on cytoplasmic tyrosines upon activation.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD307d antibody
    • Fc receptor homolog 4 antibody
    • Fc receptor like 4 antibody
    • Fc receptor like protein 4 antibody
    • Fc receptor-like protein 4 antibody
    • FcR like protein 4 antibody
    • FcR-like protein 4 antibody
    • FcRH4 antibody
    • FcRL4 antibody
    • FCRL4_HUMAN antibody
    • hIFGP2 antibody
    • IFGP family protein 2 antibody
    • IGFP2 antibody
    • Immune receptor translocation associated protein 1 antibody
    • Immune receptor translocation-associated protein 1 antibody
    • Immunoglobulin superfamily receptor translocation associated 1 antibody
    • Immunoglobulin superfamily receptor translocation associated gene 1 antibody
    • IRTA1 antibody
    see all

Images

  • Anti-FCRL4 antibody (ab98279) at 1 µg/ml + 293T cell lysate at 10 µg

    Predicted band size : 57 kDa

References

ab98279 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab98279.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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