Overview

  • Product nameAnti-FDPS antibody [EPR4628]
    See all FDPS primary antibodies
  • Description
    Rabbit monoclonal [EPR4628] to FDPS
  • Tested applicationsSuitable for: WB, IHC-P, Flow Cytmore details
    Unsuitable for: ICC or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to residues near the C-terminus of Human FDPS.

  • Positive control
    • THP1, HepG2, and Human fetal liver lysates; Human kidney tissue.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

Properties

Applications

Our Abpromise guarantee covers the use of ab109007 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 48 kDa.
IHC-P 1/100 - 1/250. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Heat up to 98 degrees C, below boiling, and then let cool for 10-20 min.
Flow Cyt 1/10 - 1/100. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • Application notesIs unsuitable for ICC or IP.
  • Target

    • FunctionKey enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
    • PathwayIsoprenoid biosynthesis; farnesyl diphosphate biosynthesis; farnesyl diphosphate from geranyl diphosphate and isopentenyl diphosphate: step 1/1.
      Isoprenoid biosynthesis; geranyl diphosphate biosynthesis; geranyl diphosphate from dimethylallyl diphosphate and isopentenyl diphosphate: step 1/1.
    • Sequence similaritiesBelongs to the FPP/GGPP synthase family.
    • Cellular localizationCytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • (2E antibody
      • (2E,6E) farnesyl diphosphate synthase antibody
      • 6E)-farnesyl diphosphate synthase antibody
      • Dimethylallyltranstransferase antibody
      • Farnesyl diphosphate synthase antibody
      • Farnesyl diphosphate synthetase antibody
      • Farnesyl pyrophosphate synthase antibody
      • Farnesyl pyrophosphate synthetase antibody
      • Fdps antibody
      • FPP synthase antibody
      • FPP synthetase antibody
      • FPPS antibody
      • FPPS_HUMAN antibody
      • FPS antibody
      • Geranyltranstransferase antibody
      see all

    Anti-FDPS antibody [EPR4628] images

    • All lanes : Anti-FDPS antibody [EPR4628] (ab109007) at 1/1000 dilution

      Lane 1 : THP1 cell lysates
      Lane 2 : HepG2 cell lysates
      Lane 3 : Human fetal liver lysates


      Predicted band size : 48 kDa
    • ab109007 at 1/100 dilution staining FDPS in Human kidney by Immunohistochemistry, Paraffin-embedded tissue.

    References for Anti-FDPS antibody [EPR4628] (ab109007)

    ab109007 has not yet been referenced specifically in any publications.

    Product Wall

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"