Anti-Feline MHC Class II antibody [vpg 3] (ab34028)

Overview

  • Product name
    Anti-Feline MHC Class II antibody [vpg 3]
  • Description
    Mouse monoclonal [vpg 3] to Feline MHC Class II
  • Host species
    Mouse
  • Specificity
    ab34028 recognises MHC Class II antigens
  • Tested applications
    Suitable for: Flow Cyt, IHC-Fr, IPmore details
    Unsuitable for: IHC-P
  • Species reactivity
    Reacts with: Cat
    Does not react with: Human
  • Immunogen

    Tissue/ cell preparation of IL2 dependent feline T cells

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: 5-10% Foetal calf serum, Tissue culture supernatant, 0.2M Tris HCl. pH 7.4
  • Purity
    Tissue culture supernatant
  • Clonality
    Monoclonal
  • Clone number
    vpg 3
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab34028 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
IHC-Fr
IP
  • Application notes
    FACS: Use 50µl for 106 cells in 100µl.
    IHC-Fr: Use at an assay dependent dilution.
    IP: Use at an assay dependent dilution.

    Is unsuitable for IHC-P.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance
      HLA-DRB1 belongs to the HLA class II beta chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells including B lymphocytes, dendritic cells and macrophages.
    • Cellular localization
      single-pass type I membrane protein
    • Database links
    • Alternative names
      • DR 1 antibody
      • MHC class II histocompatability antigen antibody

    References

    ab34028 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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