Overview

  • Product name
  • Description
    Goat polyclonal to FEM 1C
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide: HIPEKLETFVSLHR, corresponding to C terminal amino acids 604-617 of Human FEM 1C.

  • Positive control
    • HeLa cell lysate
  • General notes


    A caspase substrate homologous to the Caenorhabditis elegans sex-determining protein, FEM-1. Principle Names - FEM1A; feminization 1 homolog a; KIAA1785; EUROIMAGE686608; EUROIMAGE783647

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, 5mg/ml Tris, pH 7.3
  • Concentration information loading...
  • Purity
    IgG fraction
  • Purification notes
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Primary antibody notes
    A caspase substrate homologous to the Caenorhabditis elegans sex-determining protein, FEM-1. Principle Names - FEM1A; feminization 1 homolog a; KIAA1785; EUROIMAGE686608; EUROIMAGE783647
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab9207 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 75 kDa (predicted molecular weight: 69 kDa).Can be blocked with Human FEM 1C peptide (ab23153).

Target

  • Function
    Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit.
  • Tissue specificity
    Widely expressed. Highly expressed in kidney, cardiac tissue, skeletal muscle and testis. Expressed at lower levels in other tissues, including cartilage.
  • Pathway
    Protein modification; protein ubiquitination.
  • Sequence similarities
    Belongs to the fem-1 family.
    Contains 9 ANK repeats.
    Contains 2 TPR repeats.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • EUROIMAGE686608 antibody
    • EUROIMAGE783647 antibody
    • fem1 homolog c (C. elegans) antibody
    • FEM1-gamma antibody
    • FEM1A antibody
    • FEM1c antibody
    • FEM1C_HUMAN antibody
    • Feminization 1 homolog a antibody
    • KIAA1785 antibody
    • Protein fem-1 homolog C antibody
    see all

Images

References

ab9207 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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