Overview

  • Product name
    Anti-FER antibody - C-terminal
    See all FER primary antibodies
  • Description
    Rabbit polyclonal to FER - C-terminal
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide from the C-terminal region of human FER conjugated to KLH.

  • Positive control
    • HL-60 cell lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Protein G purified
  • Purification notes
    ab71682 is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab71682 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 100 kDa (predicted molecular weight: 93 kDa).

Target

  • Function
    Tyrosine kinase of the non-receptor type. Probably performs an important function, perhaps in regulatory processes such as cell cycle control.
  • Tissue specificity
    Expressed in a variety of lymphoid cell lines.
  • Sequence similarities
    Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
    Contains 1 FCH domain.
    Contains 1 protein kinase domain.
    Contains 1 SH2 domain.
  • Cellular localization
    Cytoplasm. Nucleus. Associated with the chromatin.
  • Information by UniProt
  • Database links
  • Alternative names
    • c FER antibody
    • Feline encephalitis virus related kinase FER antibody
    • Fer (fps/fes related) tyrosine kinase (phosphoprotein NCP94) antibody
    • Fer (fps/fes related) tyrosine kinase antibody
    • FER antibody
    • FER_HUMAN antibody
    • FerT antibody
    • Fujinami poultry sarcoma/Feline sarcoma related protein Fer antibody
    • p94 FER antibody
    • p94-FER antibody
    • Pe1Fe10 antibody
    • Pe1Fe13 antibody
    • Pe1Fe3 antibody
    • Pe1Fe6 antibody
    • Phosphoprotein NCP94 antibody
    • PPP1R74 antibody
    • Protein phosphatase 1 regulatory subunit 74 antibody
    • Proto oncogene tyrosine protein kinase FER antibody
    • Proto-oncogene c-Fer antibody
    • TYK3 antibody
    • Tyrosine kinase 3 antibody
    • Tyrosine-protein kinase Fer antibody
    see all

Images

  • Anti-FER antibody - C-terminal (ab71682) at 1/100 dilution + HL-60 cell lysate at 12.5 µg

    Predicted band size : 93 kDa
    Observed band size : 100 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 50 kDa,75 kDa. We are unsure as to the identity of these extra bands.

References

This product has been referenced in:
  • Zoubeidi A  et al. The Fer tyrosine kinase cooperates with interleukin-6 to activate signal transducer and activator of transcription 3 and promote human prostate cancer cell growth. Mol Cancer Res 7:142-55 (2009). Read more (PubMed: 19147545) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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