The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/3000. Predicted molecular weight: 54 kDa.
Use at an assay dependent concentration.
Serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.
Steroid metabolism; cholesterol metabolism.
Belongs to the ferredoxin--NADP reductase type 1 family.