Overview

  • Product nameAnti-Ferredoxin Reductase antibody
    See all Ferredoxin Reductase primary antibodies
  • Description
    Rabbit polyclonal to Ferredoxin Reductase
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant fragment derived from amino acid 250 to the C terminus of human Ferredoxin Reductase. A C-terminal His tag was added to the antigen.

  • Positive control
    • HeLa cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab16874 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/3000. Predicted molecular weight: 55 kDa.

Target

  • FunctionServes as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.
  • PathwaySteroid metabolism; cholesterol metabolism.
  • Sequence similaritiesBelongs to the ferredoxin--NADP reductase type 1 family.
  • Cellular localizationMitochondrion matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • Adrenodoxin reductase antibody
    • ADRO_HUMAN antibody
    • ADXR antibody
    • AR antibody
    • FDXR antibody
    • Ferredoxin NADP(+) reductase antibody
    • Ferredoxin reductase antibody
    • Ferredoxin--NADP(+) reductase antibody
    • mitochondrial antibody
    • NADPH adrenodoxin oxidoreductase mitochondrial antibody
    • NADPH:adrenodoxin oxidoreductase antibody
    see all

Anti-Ferredoxin Reductase antibody images



  • Predicted band size : 55 kDa


    ab16874 (1/500) detection of Ferredoxin Reductase in HeLa cell lysates.

    Lane 1: HeLa cell lysate
    Lane 2: mouse lung
    Lane 3: rat lung

    We do not know the identity of the lower band seen in the mouse and rat lysates.

References for Anti-Ferredoxin Reductase antibody (ab16874)

This product has been referenced in:
  • Li J  et al. De novo synthesis of steroids and oxysterols in adipocytes. J Biol Chem 289:747-64 (2014). WB . Read more (PubMed: 24280213) »
  • Pichiorri F  et al. Correlation of fragile histidine triad (Fhit) protein structural features with effector interactions and biological functions. J Biol Chem 284:1040-9 (2009). WB ; Human . Read more (PubMed: 19004824) »

See all 4 Publications for this product

Product Wall

Thank you for your enquiry. The immunogen was derived from amino acid 250 to the C terminus. A C-terminal His tag was added to the antigen. Please do not hesitate to contact us if you need anything further.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"