Anti-Ferritin Light Chain antibody [AF7B7] (ab80617)


  • Product nameAnti-Ferritin Light Chain antibody [AF7B7]
    See all Ferritin Light Chain primary antibodies
  • Description
    Mouse monoclonal [AF7B7] to Ferritin Light Chain
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    His-tagged recombinant Human Ferritin Light Chain, expressed in E. Coli

  • Positive control
    • HeLa cells lysate.



Our Abpromise guarantee covers the use of ab80617 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/5000. Detects a band of approximately 20 kDa (predicted molecular weight: 20 kDa).


  • FunctionStores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.
  • Involvement in diseaseDefects in FTL are the cause of hereditary hyperferritinemia-cataract syndrome (HHCS) [MIM:600886]. It is an autosomal dominant disease characterized by early-onset bilateral cataract. Affected patients have elevated level of circulating ferritin. HHCS is caused by mutations in the iron responsive element (IRE) of the FTL gene.
    Defects in FTL are the cause of neurodegeneration with brain iron accumulation type 3 (NBIA3) [MIM:606159]; also known as adult-onset basal ganglia disease. It is a movement disorder with heterogeneous presentations starting in the fourth to sixth decade. It is characterized by a variety of neurological signs including parkinsonism, ataxia, corticospinal signs, mild nonprogressive cognitive deficit and episodic psychosis. It is linked with decreased serum ferritin levels.
  • Sequence similaritiesBelongs to the ferritin family.
    Contains 1 ferritin-like diiron domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • Ferritin L chain antibody
    • Ferritin L subunit antibody
    • Ferritin light chain antibody
    • Ferritin light polypeptide antibody
    • ferritin light polypeptide like 3 antibody
    • FRIL_HUMAN antibody
    • FTL antibody
    • LFTD antibody
    • NBIA 3 antibody
    • NBIA3 antibody
    see all

Anti-Ferritin Light Chain antibody [AF7B7] images

  • All lanes : Anti-Ferritin Light Chain antibody [AF7B7] (ab80617) at 1/5000 dilution

    Lane 1 : HeLa cell lysate
    Lane 2 : A431 cell lysate
    Lane 3 : HepG2 cell lysate
    Lane 4 : U937 cell lysate
    Lane 5 : Hep3B cell lysate
    Lane 6 : Jurkat cell lysate
    Lane 7 : HL60 cell lysate

    Predicted band size : 20 kDa
    Observed band size : 20 kDa

References for Anti-Ferritin Light Chain antibody [AF7B7] (ab80617)

ab80617 has not yet been referenced specifically in any publications.

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