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Read our guarantee »Products:Cardiovascular >> Blood >> Serum Proteins
Anti-fetal hemoglobin antibody
See all fetal hemoglobin products (3) ...
Sheep polyclonal to fetal hemoglobin
By immunoelectrophoresis and ELISA this antibody reacts specifically with human hemoglobin F. No antibody was detected against hemoglobin A1, A2, S or human serum proteins.
ELISA, IHC-Pmore details
Reacts with
Human
Predicted to work with
Chimpanzee, Rhesus monkey, Gorilla
Human Hemoglobin F
Liquid
Store at +4°C.
Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.2
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Immunogen affinity purified
The antibody was isolated by affinity chromato-graphy using antigen coupled to agarose beads. Antibody concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG.
Polyclonal
IgG
Cardiovascular >> Blood >> Other
Cardiovascular >> Blood >> Serum Proteins
Our Abpromise guarantee covers the use of ab19364 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA: Use at an assay dependent dilution.
IHC-P: 1/20Antigen retrieval is not essential but may optimise staining.(PubMed: 21378008)
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'
Cytoplasmic
This product has been referenced in:
See all 2 publications for this product
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