Anti-fetal hemoglobin antibody (FITC) (ab19365)

Overview

  • Product nameAnti-fetal hemoglobin antibody (FITC)
    See all fetal hemoglobin primary antibodies
  • Description
    Sheep polyclonal to fetal hemoglobin (FITC)
  • ConjugationFITC. Ex: 493nm, Em: 528nm
  • SpecificityBy immunoelectrophoresis and ELISA this antibody reacts specifically with human hemoglobin F. No antibody was detected against hemoglobin A1, A2, S or human serum proteins.
  • Tested applicationsSuitable for: ICCmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Gorilla
  • Immunogen

    Human Hemoglobin F

  • General notes

    F/P ratio is 3 to 7.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C.
  • Storage bufferPreservative: 0.1% Sodium Azide
    Constituents: 0.2% BSA, PBS, pH 7.2
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesThe antibody was isolated by affinity chromatography using antigen coupled to agarose beads. Antibody concentration was determined by extinction coefficient prior to conjugation: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab19365 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC 1/200 - 1/2000.

Target

  • RelevanceThe gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'
  • Cellular localizationCytoplasmic
  • Database links
  • Alternative names
    • A gamma globin antibody
    • G gamma globin antibody
    • Gamma 1 globin antibody
    • Gamma 2 globin antibody
    • Gamma A hemoglobin antibody
    • Gamma globin antibody
    • Hb F Agamma antibody
    • Hb F Ggamma antibody
    • hbfagamma antibody
    • hbfggamma antibody
    • HBG 1 antibody
    • HBG 2 antibody
    • HBG1 antibody
    • HBG2 antibody
    • HBGA antibody
    • HBGR antibody
    • Hemoglobin gamma 1 chain antibody
    • Hemoglobin gamma 2 chain antibody
    • Hemoglobin gamma A antibody
    • Hemoglobin gamma A chain antibody
    • Hemoglobin gamma G antibody
    • Hemoglobin gamma G chain antibody
    • Hemoglobin gamma regulator of antibody
    • Hemoglobin subunit gamma 1 antibody
    • Hemoglobin subunit gamma 2 antibody
    • HSGGL 1 antibody
    • HSGGL1 antibody
    • Methemoglobin antibody
    • PRO 2979 antibody
    • PRO2979 antibody
    see all

References for Anti-fetal hemoglobin antibody (FITC) (ab19365)

ab19365 has not yet been referenced specifically in any publications.

Product Wall



This antibody was generated against a whole hemoglobin prep’, and does not allow discrimination between the tetramer and subunits. As a true polyclonal antibody, there may be one or more members of the clonal “pool” which bi...

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DISCOUNT CODE: XXXXXXXX
Expiration date: 29-05-2013
Value: £235

I am very pleased to hear you would like to accept our offer and test ab19365 in Flow Cytometry. This code will give you £235 off your next order before the ex...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"