Anti-fetal hemoglobin antibody (HRP) (ab19366)

Overview

  • Product nameAnti-fetal hemoglobin antibody (HRP)
    See all fetal hemoglobin primary antibodies
  • Description
    Sheep polyclonal to fetal hemoglobin (HRP)
  • ConjugationHRP
  • SpecificityBy immunoelectrophoresis and ELISA this antibody reacts specifically with human hemoglobin F. No antibody was detected against hemoglobin A1, A2, S or human serum proteins.
  • Tested applicationsSuitable for: ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Hemoglobin purified from cord blood (Human).

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C.
  • Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
    Constituents: 0.2% BSA, 0.1M Sodium chloride, 50mM HEPES. pH 7.1
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab19366 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/10000 - 1/100000.

Target

  • RelevanceThe gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'
  • Cellular localizationCytoplasmic
  • Database links
  • Alternative names
    • A gamma globin antibody
    • G gamma globin antibody
    • Gamma 1 globin antibody
    • Gamma 2 globin antibody
    • Gamma A hemoglobin antibody
    • Gamma globin antibody
    • Hb F Agamma antibody
    • Hb F Ggamma antibody
    • hbfagamma antibody
    • hbfggamma antibody
    • HBG 1 antibody
    • HBG 2 antibody
    • HBG1 antibody
    • HBG2 antibody
    • HBGA antibody
    • HBGR antibody
    • Hemoglobin gamma 1 chain antibody
    • Hemoglobin gamma 2 chain antibody
    • Hemoglobin gamma A antibody
    • Hemoglobin gamma A chain antibody
    • Hemoglobin gamma G antibody
    • Hemoglobin gamma G chain antibody
    • Hemoglobin gamma regulator of antibody
    • Hemoglobin subunit gamma 1 antibody
    • Hemoglobin subunit gamma 2 antibody
    • HSGGL 1 antibody
    • HSGGL1 antibody
    • Methemoglobin antibody
    • PRO 2979 antibody
    • PRO2979 antibody
    see all

References for Anti-fetal hemoglobin antibody (HRP) (ab19366)

ab19366 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"