Overview

  • Product name
  • Description
    Rabbit polyclonal to FFAR3
  • Specificity
    BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Gorilla
  • Immunogen

    A 16 amino acid synthetic peptide corresponding to the internal region of Human FFAR3 (NP_005295.1).

  • Positive control
    • Human liver and Human adrenal tissues

Properties

Applications

Our Abpromise guarantee covers the use of ab150483 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Requires pretreatment with Proteinase K.

Target

  • Function
    Receptor for short chain fatty acids. The activity of this receptor is coupled to the formation of inositol 1,4,5-trisphosphate, intracellular Ca2+ mobilization, the activation of ERK 1/2 and inhibition of intracellular cAMP accumulation. Coupled exclusively to the pertussis toxin-sensitive G(i/o)-alpha protein. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate.
  • Tissue specificity
    Highest level in adipose tissue, and lower expression across all tissues tested.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • FFA3R antibody
    • Ffar3 antibody
    • FFAR3_HUMAN antibody
    • Free fatty acid receptor 3 antibody
    • G protein coupled receptor 41 antibody
    • G-protein coupled receptor 41 antibody
    • gpcr41 antibody
    • GPR41 antibody
    • gpr42 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin embedded Human liver tissue labelling FFAR3 with ab150483 antibody at a concentration of 5 µg/ml.
  • Immunohistochemical analysis of paraffin embedded Human adrenal tissue labelling FFAR3 with ab150483 antibody at a concentration of 5 µg/ml.

References

ab150483 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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