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Rabbit polyclonal to FGD1
HumanPredicted to work with:
Cow, Cat, Dog, Pig
Synthetic peptide, corresponding to a region within N terminal amino acids 2-51 (HGHRAPGGAG PSEPEHPATN PPGAAPPACA DSDPGASEPG LLARRGSGSA) of Human FGD1 (NP_004454).
- Transfected 293T cell lysate.
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Constituents: 2% Sucrose, PBS
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 1 µg/ml. Predicted molecular weight: 107 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape.
Expressed in fetal heart, brain, lung, kidney and placenta. Less expressed in liver; adult heart, brain, lung, pancreas and skeletal muscle.
Involvement in disease
Defects in FGD1 are found in a patient with non-syndromal X-linked mental retardation.
Contains 1 DH (DBL-homology) domain.
Contains 1 FYVE-type zinc finger.
Contains 2 PH domains.
The DH domain is involved in interaction with CCPG1.
Cytoplasm. Cell projection, lamellipodium. Cell projection, ruffle. Cytoplasm, cytoskeleton. Associated with membrane ruffles and lamellipodia.
Information by UniProt
- AAS antibody
- Faciogenital dysplasia 1 protein antibody
- FGD1 antibody
has not yet been referenced specifically in any publications.
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