Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab58311 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-P
  • Application notesWB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionThe heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro.
    • Sequence similaritiesBelongs to the heparin-binding growth factors family.
    • Cellular localizationSecreted. Cytoplasm. Cytoplasm > cell cortex. Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1.
    • Information by UniProt
    • Database links
    • Alternative names
      • Acidic fibroblast growth factor antibody
      • aFGF antibody
      • Beta endothelial cell growth factor antibody
      • Beta-endothelial cell growth factor antibody
      • ECGF antibody
      • ECGF beta antibody
      • ECGF-beta antibody
      • ECGFA antibody
      • ECGFB antibody
      • Endothelial Cell Growth Factor alpha antibody
      • Endothelial Cell Growth Factor beta antibody
      • FGF 1 antibody
      • FGF alpha antibody
      • Fgf1 antibody
      • FGF1_HUMAN antibody
      • FGFA antibody
      • Fibroblast Growth Factor 1 Acidic antibody
      • Fibroblast growth factor 1 antibody
      • GLIO703 antibody
      • HBGF 1 antibody
      • HBGF-1 antibody
      • HBGF1 antibody
      • Heparin binding growth factor 1 antibody
      • Heparin binding growth factor 1 precursor antibody
      • Heparin-binding growth factor 1 antibody
      see all

    Anti-FGF1 antibody images

    • FGF1 antibody (ab58311) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human spleen.
    • Western blot against tagged recombinant protein immunogen using ab58311 FGF1 antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa

    References for Anti-FGF1 antibody (ab58311)

    ab58311 has not yet been referenced specifically in any publications.

    Product Wall

    I now have a bit more information to share with you. As discussed, Anti-FGF1 (ab58311) is raised against a fusion protein of FGF1 (with a well know purification tag) of ~45 kDa, and it is this fusion protein which has been expressed and detected in the...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"