Anti-FGF19 antibody (ab119336)
Key features and details
- Rabbit polyclonal to FGF19
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-FGF19 antibody
See all FGF19 primary antibodies -
Description
Rabbit polyclonal to FGF19 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide, corresponding to a sequence in the middle region of Human FGF19.
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Positive control
- WB: U87 and SMMC whole cell lysate. IHC: Human Gallbladder Cancer Tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
Preservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab119336 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 0.5 µg/ml. Predicted molecular weight: 24 kDa.
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IHC-P |
Use a concentration of 1 µg/ml.
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Notes |
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WB
Use a concentration of 0.5 µg/ml. Predicted molecular weight: 24 kDa. |
IHC-P
Use a concentration of 1 µg/ml. |
Target
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Function
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB. -
Tissue specificity
Expressed in fetal brain, cartilage, retina, and adult gall bladder. -
Sequence similarities
Belongs to the heparin-binding growth factors family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 9965 Human
- NCBI: NM_005117 Human
- Omim: 603891 Human
- SwissProt: O95750 Human
- Unigene: 249200 Human
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Alternative names
- FGF 19 antibody
- FGF-19 antibody
- FGF15 antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab119336 has been referenced in 1 publication.
- Unal HU et al. Lack of relationships between FGF19 staining pattern, lymph node metastasis and locally invasive characteristics of the tumor in colorectal cancers. Asian Pac J Cancer Prev 14:3151-4 (2013). PubMed: 23803094