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  • Product nameAnti-FGF basic antibody
    See all FGF basic primary antibodies
  • Description
    Rabbit polyclonal to FGF basic
  • Tested applicationsNeutralising, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human FGF basic aa 58-210.
    Database link: P09038



Our Abpromise guarantee covers the use of ab11937 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Neutralising Use a concentration of 3.5 µg/ml.

Use at a concentration of 3.5 µg/ml to yield one-half maximal inhibition [ND50] of the biological activity of human FGF basic (FGF2) (5ng/ml) on HUVEC cells.

WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 30 kDa.


  • FunctionPlays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.
  • Tissue specificityExpressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non-cancerous liver tissue.
  • Sequence similaritiesBelongs to the heparin-binding growth factors family.
  • Post-translational
    Phosphorylation at Tyr-215 regulates FGF2 unconventional secretion.
    Several N-termini starting at positions 94, 125, 126, 132, 143 and 162 have been identified by direct sequencing.
  • Cellular localizationSecreted. Nucleus. Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism. Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane. Binding of exogenous FGF2 to FGFR facilitates endocytosis followed by translocation of FGF2 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as CEP57.
  • Information by UniProt
  • Database links
  • Alternative names
    • Basic fibroblast growth factor antibody
    • Basic fibroblast growth factor bFGF antibody
    • BFGF antibody
    • FGF 2 antibody
    • FGF B antibody
    • FGF-2 antibody
    • Fgf2 antibody
    • FGF2 basic antibody
    • FGF2_HUMAN antibody
    • FGFB antibody
    • Fibroblast growth factor 2 (basic) antibody
    • Fibroblast growth factor 2 antibody
    • Fibroblast growth factor, basic antibody
    • HBGF 2 antibody
    • HBGF-2 antibody
    • HBGF2 antibody
    • HBGH 2 antibody
    • HBGH2 antibody
    • Heparin binding growth factor 2 precursor antibody
    • Heparin-binding growth factor 2 antibody
    • Prostatropin antibody
    see all

Anti-FGF basic antibody images

  • All lanes : Anti-FGF2 antibody (ab11937)

    Lane 1 : Recombinant fragment human FGF basic
    Lane 2 : Recombinant fragment mouse FGF basic
    Lane 3 : Recombinant fragment rat FGF basic

    Predicted band size : 30 kDa

References for Anti-FGF basic antibody (ab11937)

ab11937 has not yet been referenced specifically in any publications.

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