Overview

  • Product nameAnti-FGF3 antibody [MSD1]
    See all FGF3 primary antibodies
  • Description
    Mouse monoclonal [MSD1] to FGF3
  • Tested applicationsSuitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Human, Xenopus laevis
  • Immunogen

    Synthetic peptide: RRTQKSSLFLPRVL. FGF3 conjugated to BSA, corresponding to amino acids 170-183 of Human FGF3.

Properties

Applications

Our Abpromise guarantee covers the use of ab10830 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ICC/IF
  • Application notesICC/IF: Use at an assay dependent dilution. Fixation in 4% paraformaldehyde in PBS for 20 min.
    WB: Use at an assay dependent dilution. Predicted molecular weight: 29 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceFibroblast growth factors (FGFs) can stimulate the proliferation of mesenchymal, epithelial and neuroectodermal cells. FGF3 belongs to the heparin binding growth factors family. Members of the family include Acidic FGF (also known as aFGF or FGF 1), basic FGF (bFGF or FGF 2), FGF 3 (also known as Int2) and FGF 4 (also known as hst or Kaposi FGF). FGF 4 was first revealed to be an oncoprotein in Kaposi's sarcoma cells. Other family members include FGF 5, FGF 6, FGF 7 (keratinocyte growth factor, KGF), FGF 8 (AIGF), FGF 9 (GAF) and FGF 10. FGF3 is activated by proviral insertion of mouse mammary tumor virus (MMTV). FGF3 is responsible for most of breast malignancies.
    • Cellular localizationSecreted.
    • Database links
    • Alternative names
      • FGF 3 antibody
      • Fibroblast growth factor 3 antibody
      • HBGF 3 antibody
      • HBGF3 antibody
      • INT 2 antibody
      • INT 2 proto oncogene protein antibody
      • INT 2 proto oncogene protein precurosr antibody
      • INT2 antibody
      • INT2 proto oncogene protein precurosr antibody
      • Murine mammary tumor virus integration site (v int 2) oncogene homolog antibody
      • Murine mammary tumor virus integration site 2 antibody
      • Oncogene INT2 antibody
      • V INT2 murine mammary tumor virus integration site oncogene homolog antibody
      see all

    References for Anti-FGF3 antibody [MSD1] (ab10830)

    This product has been referenced in:
    • Xiao W  et al. Upregulation of miR-31* Is Negatively Associated with Recurrent/Newly Formed Oral Leukoplakia. PLoS One 7:e38648 (2012). WB ; Human . Read more (PubMed: 22719913) »
    • Giatromanolaki A  et al. DEC1 (STRA13) protein expression relates to hypoxia- inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer. J Pathol 200:222-8 (2003). Read more (PubMed: 12754744) »

    See all 3 Publications for this product

    Product Wall

    Thank you for getting back to me. I appreciate your frustration. Please let me apologise for the lack of a recommended dilution for this antibody by immunofluorescence and the cited publication which I conceded does not reference this antibody. I have ...

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    Thank you for your enquiry. I am sorry but we do not have any further information as to a recommended dilution for this antibody. I would like to recommend that you contact Michael I Koukourakis given that they applied this antibody. According to t...

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    Thank you for your enquiry and your patience in awaiting a response. Unfortunately, we are not aware of a tissue that expresses reasonable levels of Fgf3.The antibody has been tested on whole embryos, as they express Fgf-3 (as determined by in situ) at...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"