Overview

  • Product name
    Anti-FGF9 antibody (Biotin)
    See all FGF9 primary antibodies
  • Description
    Rabbit polyclonal to FGF9 (Biotin)
  • Conjugation
    Biotin
  • Tested applications
    Suitable for: ELISA, Sandwich ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Highly pure (>98%) recombinant mouse FGF9.

Properties

Applications

Our Abpromise guarantee covers the use of ab84274 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
Sandwich ELISA
WB
  • Application notes
    ELISA: Use at a concentration of 0.25 - 1 µg/ml. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant mouse FGF9.
    sELISA: Use at a concentration of 0.25 - 1 µg/ml. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant mouse FGF9.
    WB: Use at a concentration of 0.1 - 0.2 µg/ml. The detection limit for recombinant mouse FGF9 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions. Predicted molecular weight: 23 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.
    • Tissue specificity
      Glial cells.
    • Involvement in disease
      Defects in FGF9 are the cause of multiple synostoses syndrome type 3 (SYNS3) [MIM:612961]. Multiple synostoses syndrome is an autosomal dominant condition characterized by progressive joint fusions of the fingers, wrists, ankles and cervical spine, characteristic facies and progressive conductive deafness.
    • Sequence similarities
      Belongs to the heparin-binding growth factors family.
    • Post-translational
      modifications
      Three molecular species were found (30 kDa, 29 kDa and 25 kDa), cleaved at Leu-4, Val-13 and Ser-34 respectively. The smaller ones might be products of proteolytic digestion. Furthermore, there may be a functional signal sequence in the 30 kDa species which is uncleavable in the secretion step.
      N-glycosylated.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • FGF 9 antibody
      • FGF-9 antibody
      • FGF9 antibody
      • FGF9_HUMAN antibody
      • Fibroblast growth factor 9 antibody
      • GAF (Glia-activafibroblast growth factor 9 (glia-activating factor) antibody
      • GAF antibody
      • Glia Activating Factor antibody
      • Glia-activating factor antibody
      • HBFG 9 antibody
      • HBFG9 antibody
      • HBGF-9 antibody
      • Heparin-binding growth factor 9 antibody
      • MGC119914 antibody
      • MGC119915 antibody
      • SYNS3 antibody
      see all

    References

    ab84274 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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