Recombinant
RabMAb

Anti-FGFR1 Oncogene Partner antibody [EPR9929] (ab156013)

Overview

  • Product name
    Anti-FGFR1 Oncogene Partner antibody [EPR9929]
    See all FGFR1 Oncogene Partner primary antibodies
  • Description
    Rabbit monoclonal [EPR9929] to FGFR1 Oncogene Partner
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IP, Flow Cyt, ICC/IFmore details
    Unsuitable for: IHC-P
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human FGFR1 Oncogene Partner (UniProt O95684).

  • Positive control
    • HeLa, 293T and Saos-2 cell lysates; HeLa cells.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab156013 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 43 kDa.
IP 1/10 - 1/100.
Flow Cyt 1/100 - 1/500.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

ICC/IF 1/100 - 1/250.
  • Application notes
    Is unsuitable for IHC-P.
  • Target

    • Function
      Required for anchoring microtubules to the centrosomes.
    • Tissue specificity
      Ubiquitous. Highly expressed in heart, liver, muscle, kidney, intestine, colon, adrenal gland, prostate, testis, and pancreas.
    • Involvement in disease
      Note=A chromosomal aberration involving FGFR1OP may be a cause of stem cell myeloproliferative disorder (MPD). Translocation t(6;8)(q27;p11) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion proteins FGFR1OP-FGFR1 or FGFR1-FGFR1OP may exhibit constitutive kinase activity and be responsible for the transforming activity.
    • Sequence similarities
      Belongs to the FGFR1OP family.
      Contains 1 LisH domain.
    • Cellular localization
      Cytoplasm > cytoskeleton > centrosome. Associated with gamma-tubulin.
    • Information by UniProt
    • Database links
    • Alternative names
      • FGFR1 oncogene partner antibody
      • FGFR1OP antibody
      • Fibroblast growth factor receptor 1 oncogene partner antibody
      • FOP antibody
      • FR1OP_HUMAN antibody
      • OTTHUMP00000017612 antibody
      • OTTHUMP00000017613 antibody
      see all

    Images

    • All lanes : Anti-FGFR1 Oncogene Partner antibody [EPR9929] (ab156013) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : 293T cell lysate
      Lane 3 : Saos-2 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 43 kDa

    • Immunofluorescent analysis of HeLa cells labeling FGFR1 Oncogene Partner with ab156013 at 1/100 dilution.

    References

    ab156013 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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