Overview

  • Product nameAnti-FGGY antibody
    See all FGGY primary antibodies
  • Description
    Rabbit polyclonal to FGGY
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Dog, Human, Pig, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 128-177 (NETKHRVLQY VGGVMSVEMQ APKLLWLKEN LREICWDKAG HFFDLPDFLS) of Mouse FGGY carbohydrate kinase domain containing, isoform 2 (NP_083623).

  • Positive control
    • Mouse kidney lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab116090 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 42 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Tissue specificityExpressed in kidney, lung and small intestine and to a lower extent in liver and detected in cerebrospinal fluid (at protein level).
  • Involvement in diseaseDefects in FGGY are associated with sporadic amyotrophic lateral sclerosis (ALS) [MIM:105400]. Amyotrophic lateral sclerosis is a neurodegenerative disorder affecting upper and lower motor neurons and resulting in fatal paralysis. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. The etiology of amyotrophic lateral sclerosis is likely to be multifactorial, involving both genetic and environmental factors.
  • Sequence similaritiesBelongs to the FGGY kinase family.
  • Developmental stageExpressed in fetal brain (at protein level).
  • Information by UniProt
  • Database links
  • Alternative names
    • fggy antibody
    • FGGY carbohydrate kinase domain containing antibody
    • FGGY carbohydrate kinase domain-containing protein antibody
    • FGGY_HUMAN antibody
    • FLJ10986 antibody
    • MGC94804 antibody
    • OTTHUMP00000010078 antibody
    • OTTHUMP00000010081 antibody
    • OTTHUMP00000010082 antibody
    • OTTHUMP00000202071 antibody
    • RP11-242B9.1 antibody
    see all

Anti-FGGY antibody images

  • Anti-FGGY antibody (ab116090) at 1 µg/ml + Mouse kidney lysate at 10 µg

    Predicted band size : 42 kDa

References for Anti-FGGY antibody (ab116090)

ab116090 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Sample Mouse Cell lysate - other (MEF, C2C12)
Loading amount 25 µg
Specification MEF, C2C12
Gel Running Conditions Reduced Denaturing
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
Username

Abcam user community

Verified customer

Submitted Aug 23 2012

Abcam has not validated the combination of species/application used in this Abreview.
Application Western blot
Sample Human Cell lysate - whole cell (HepG2, 293T)
Loading amount 25 µg
Specification HepG2, 293T
Gel Running Conditions Reduced Denaturing
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
Username

Abcam user community

Verified customer

Submitted Aug 23 2012

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"