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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer pH: 7.4 Constituent: PBS
Concentration information loading...
Purity Protein A purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Predicted molecular weight: 127 kDa.
Use a concentration of 13 µg/ml.
Function Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation.
Tissue specificity Ubiquitous. Highly expressed in spleen.
Sequence similarities Belongs to the formin homology family. Contains 1 FH1 (formin homology 1) domain. Contains 1 FH2 (formin homology 2) domain. Contains 1 GBD/FH3 (Rho GTPase-binding/formin homology 3) domain.
Domain Regulated by intramolecular binding to a C-terminal auto-inhibitory domain. Effector binding abolishes this interaction and activates the protein.
Cellular localization Cytoplasm. Cytoplasm > cytoskeleton. Predominantly cytoplasmic.
Information by UniProt
FH1/FH2 domain containing protein antibody
FH1/FH2 domain containing protein 1 antibody
FH1/FH2 domain-containing protein 1 antibody
Anti-FHOD1 antibody images
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