Anti-Fibrinopeptide B antibody - C-terminal (ab86572)


  • Product name
    Anti-Fibrinopeptide B antibody - C-terminal
    See all Fibrinopeptide B primary antibodies
  • Description
    Rabbit polyclonal to Fibrinopeptide B - C-terminal
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide derived from the C-terminal region of Human Fibrinopeptide B, conjugated to KLH

  • Positive control
    • Mouse liver tissue lysate


  • Form
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Ammonium Sulphate Precipitation
  • Clonality
  • Isotype
  • Research areas


Our Abpromise guarantee covers the use of ab86572 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Predicted molecular weight: 56 kDa.
ELISA 1/1000.


  • Function
    Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation.
  • Involvement in disease
    Defects in FGB are a cause of thrombophilia.
    Defects in FGB are a cause of congenital afibrinogenemia (CAFBN) [MIM:202400]. This rare autosomal recessive disorder is characterized by bleeding that varies from mild to severe and by complete absence or extremely low levels of plasma and platelet fibrinogen.
  • Sequence similarities
    Contains 1 fibrinogen C-terminal domain.
  • Domain
    A long coiled coil structure formed by 3 polypeptide chains connects the central nodule to the C-terminal domains (distal nodules). The long C-terminal ends of the alpha chains fold back, contributing a fourth strand to the coiled coil structure.
  • Post-translational
    Conversion of fibrinogen to fibrin is triggered by thrombin, which cleaves fibrinopeptides A and B from alpha and beta chains, and thus exposes the N-terminal polymerization sites responsible for the formation of the soft clot. The soft clot is converted into the hard clot by factor XIIIA which catalyzes the epsilon-(gamma-glutamyl)lysine cross-linking between gamma chains (stronger) and between alpha chains (weaker) of different monomers.
  • Cellular localization
  • Information by UniProt
  • Database links
  • Alternative names
    • Epididymis secretory sperm binding protein Li 78p antibody
    • FGB antibody
    • FIBB_HUMAN antibody
    • Fibrinogen B beta polypeptide antibody
    • Fibrinogen beta chain antibody
    • Fibrinogen beta polypeptide chain antibody
    • Fibrinopeptide B antibody
    • HEL S 78p antibody
    • Liver regeneration-related protein LRRG036/LRRG043/LRRG189 antibody
    • MGC104327 antibody
    • MGC120405 antibody
    • OTTHUMP00000197066 antibody
    see all

Anti-Fibrinopeptide B antibody - C-terminal images

  • Anti-Fibrinopeptide B antibody - C-terminal (ab86572) at 1/50 dilution + Mouse liver tissue lysate at 35 µg

    Predicted band size : 56 kDa

References for Anti-Fibrinopeptide B antibody - C-terminal (ab86572)

ab86572 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your email.

There are 2 antibodies involved in this experiment ab10066 and ab86572; in sELISA it will be difficult to know which antibody is failing so my suggestion would be trying, either the Indirect ELISA (by coating antigen)...

Read More

Thank you for your email. I am sorry to hear that you have been experiencing problems with this antibody.

I have read the details you have kindly provided and have following further questions for better understanding of the problem;


Read More

Thank you for contacting us.

I am sorry to hear you are experiencing difficulties with one of our products. We take product complaints very seriously, and investigate every product that we feel may not be performing correctly.

I am at...

Read More


Sign up