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ab2413 has been referenced in 95 publications.

  • Chen X  et al. The role of miR-497-5p in myofibroblast differentiation of LR-MSCs and pulmonary fibrogenesis. Sci Rep 7:40958 (2017). WB ; Mouse . PubMed: 28098218
  • Zhao W  et al. Mechanisms responsible for the inhibitory effects of epothilone B on scar formation after spinal cord injury. Neural Regen Res 12:478-485 (2017). IHC ; Rat . PubMed: 28469665
  • Konen J  et al. Image-guided genomics of phenotypically heterogeneous populations reveals vascular signalling during symbiotic collective cancer invasion. Nat Commun 8:15078 (2017). WB, ICC/IF ; Human . PubMed: 28497793
  • Bi Y  et al. MicroRNA-7 functions as a tumor-suppressor gene by regulating ILF2 in pancreatic carcinoma. Int J Mol Med 39:900-906 (2017). WB ; Human . PubMed: 28259961
  • Muranen T  et al. Starved epithelial cells uptake extracellular matrix for survival. Nat Commun 8:13989 (2017). Mouse, Human . PubMed: 28071763
  • Heim JB  et al. Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix. Proc Natl Acad Sci U S A 114:3933-3938 (2017). IHC-Fr ; Mouse, Human . PubMed: 28348210
  • Corciulo C  et al. Endogenous adenosine maintains cartilage homeostasis and exogenous adenosine inhibits osteoarthritis progression. Nat Commun 8:15019 (2017). Mouse, Rat . PubMed: 28492224
  • Llobet L  et al. Pharmacologic concentrations of linezolid modify oxidative phosphorylation function and adipocyte secretome. Redox Biol 13:244-254 (2017). WB . PubMed: 28600981
  • Voges HK  et al. Development of a human cardiac organoid injury model reveals innate regenerative potential. Development 144:1118-1127 (2017). PubMed: 28174241
  • Koo JB  et al. Anti-fibrogenic effect of PPAR-? agonists in human intestinal myofibroblasts. BMC Gastroenterol 17:73 (2017). PubMed: 28592228
  • Freeman R  et al. Instructing cells with programmable peptide DNA hybrids. Nat Commun 8:15982 (2017). PubMed: 28691701
  • Wang A  et al. Tumor-associated macrophages promote Ezrin phosphorylation-mediated epithelial-mesenchymal transition in lung adenocarcinoma through FUT4/LeY up-regulation. Oncotarget 8:28247-28259 (2017). PubMed: 28423676
  • Qiao Y  et al. Resveratrol ameliorates diabetic nephropathy in rats through negative regulation of the p38 MAPK/TGF-ß1 pathway. Exp Ther Med 13:3223-3230 (2017). PubMed: 28588674
  • Wu Y  et al. Renalase Protects against Renal Fibrosis by Inhibiting the Activation of the ERK Signaling Pathways. Int J Mol Sci 18:N/A (2017). PubMed: 28448446
  • Lachowski D  et al. Substrate Rigidity Controls Activation and Durotaxis in Pancreatic Stellate Cells. Sci Rep 7:2506 (2017). PubMed: 28566691
  • Ding BS  et al. HDL activation of endothelial sphingosine-1-phosphate receptor-1 (S1P1) promotes regeneration and suppresses fibrosis in the liver. JCI Insight 1:e87058 (2016). PubMed: 28018969
  • Laklai H  et al. Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nat Med 22:497-505 (2016). PubMed: 27089513
  • Gao R  et al. Rnf25/AO7 positively regulates wnt signaling via disrupting Nkd1-Axin inhibitory complex independent of its ubiquitin ligase activity. Oncotarget 7:23850-9 (2016). PubMed: 27007149
  • Robinson BK  et al. Quantitative analysis of 3D extracellular matrix remodelling by pancreatic stellate cells. Biol Open 5:875-82 (2016). PubMed: 27170254
  • Shan G  et al. Astragalus membranaceus ameliorates renal interstitial fibrosis by inhibiting tubular epithelial-mesenchymal transition in vivo and in vitro. Exp Ther Med 11:1611-1616 (2016). IHC . PubMed: 27168780
  • Xu G  et al. Defects in MAP1S-mediated autophagy turnover of fibronectin cause renal fibrosis. Aging (Albany NY) 8:977-85 (2016). PubMed: 27236336
  • Herrera C  et al. Muscle Tissue Damage Induced by the Venom of Bothrops asper: Identification of Early and Late Pathological Events through Proteomic Analysis. PLoS Negl Trop Dis 10:e0004599 (2016). PubMed: 27035343
  • Fedorenko IV  et al. Fibronectin induction abrogates the BRAF inhibitor response of BRAF V600E/PTEN-null melanoma cells. Oncogene 35:1225-35 (2016). PubMed: 26073081
  • Li S  et al. Induction of epithelial-mesenchymal transition (EMT) by Beclin 1 knockdown via posttranscriptional upregulation of ZEB1 in thyroid cancer cells. Oncotarget 7:70364-70377 (2016). WB . PubMed: 27683118
  • Li W  et al. Defects in MAP1S-mediated autophagy cause reduction in mouse lifespans especially when fibronectin is overexpressed. Aging Cell 15:370-9 (2016). PubMed: 26750654
  • Sakar MS  et al. Cellular forces and matrix assembly coordinate fibrous tissue repair. Nat Commun 7:11036 (2016). IHC . PubMed: 26980715
  • Mobin MB  et al. The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation. Nat Commun 7:12848 (2016). PubMed: 27665711
  • Li Q  et al. Hepatitis C virus depends on E-cadherin as an entry factor and regulates its expression in epithelial-to-mesenchymal transition. Proc Natl Acad Sci U S A 113:7620-5 (2016). WB, ICC/IF ; Human . PubMed: 27298373
  • Dinulovic I  et al. Muscle PGC-1a modulates satellite cell number and proliferation by remodeling the stem cell niche. Skelet Muscle 6:39 (2016). WB ; Mouse . PubMed: 27908291
  • Yang YF  et al. Effects of induction and inhibition of matrix cross-linking on remodeling of the aqueous outflow resistance by ocular trabecular meshwork cells. Sci Rep 6:30505 (2016). WB ; Human . PubMed: 27465745
  • Wang Y  et al. MicroRNA-142-3p inhibits hypoxia/reoxygenation-induced apoptosis and fibrosis of cardiomyocytes by targeting high mobility group box 1. Int J Mol Med 38:1377-1386 (2016). WB ; Mouse . PubMed: 28025989
  • Sarper M  et al. ATRA modulates mechanical activation of TGF-ß by pancreatic stellate cells. Sci Rep 6:27639 (2016). ICC/IF ; Human . PubMed: 27375161
  • Shen YL  et al. P53 inhibitor pifithrin-a prevents the renal tubular epithelial cells against injury. Am J Transl Res 8:4040-4053 (2016). Rat . PubMed: 27829991
  • Kasetti RB  et al. Expression of Mutant Myocilin Induces Abnormal Intracellular Accumulation of Selected Extracellular Matrix Proteins in the Trabecular Meshwork. Invest Ophthalmol Vis Sci 57:6058-6069 (2016). Mouse . PubMed: 27820874
  • Zhou W  et al. MicroRNA-98 acts as a tumor suppressor in hepatocellular carcinoma via targeting SALL4. Oncotarget 7:74059-74073 (2016). WB ; Human . PubMed: 27677076
  • Yi W  et al. High expression of fibronectin is associated with poor prognosis, cell proliferation and malignancy via the NF-?B/p53-apoptosis signaling pathway in colorectal cancer. Oncol Rep 36:3145-3153 (2016). IHC-P . PubMed: 27748871
  • Guo J  et al. Glycogen synthase kinase-3ß is required for epithelial-mesenchymal transition and barrier dysfunction in mouse podocytes under high glucose conditions. Mol Med Rep 14:4091-4098 (2016). WB ; Mouse . PubMed: 27748847
  • Jiang C  et al. Rescue therapy with Tanshinone IIA hinders transition of acute kidney injury to chronic kidney disease via targeting GSK3ß. Sci Rep 6:36698 (2016). IHC-P ; Mouse . PubMed: 27857162
  • Li C  et al. RhoA determines lineage fate of mesenchymal stem cells by modulating CTGF-VEGF complex in extracellular matrix. Nat Commun 7:11455 (2016). IHC (PFA fixed) . PubMed: 27126736
  • Sun H  et al. Astragaloside IV ameliorates renal injury in db/db mice. Sci Rep 6:32545 (2016). WB, IHC-P ; Mouse . PubMed: 27585918
  • Jiang M  et al. Changes in tension regulates proliferation and migration of fibroblasts by remodeling expression of ECM proteins. Exp Ther Med 12:1542-1550 (2016). WB ; Human . PubMed: 27588075
  • Zhang ZH  et al. An integrated lipidomics and metabolomics reveal nephroprotective effect and biochemical mechanism of Rheum officinale in chronic renal failure. Sci Rep 6:22151 (2016). WB ; Rat . PubMed: 26903149
  • Kimura T  et al. C-type natriuretic peptide ameliorates pulmonary fibrosis by acting on lung fibroblasts in mice. Respir Res 17:19 (2016). WB ; Mouse . PubMed: 26895702
  • Verrill C  et al. Altered expression of epithelial-to-mesenchymal transition proteins in extraprostatic prostate cancer. Oncotarget 7:1107-19 (2016). PubMed: 26701730
  • Cao YL  et al. TGF-ß1, in association with the increased expression of connective tissue growth factor, induce the hypertrophy of the ligamentum flavum through the p38 MAPK pathway. Int J Mol Med 38:391-8 (2016). ICC/IF ; Human . PubMed: 27279555
  • Jeong SY  et al. Co-Culture of Tumor Spheroids and Fibroblasts in a Collagen Matrix-Incorporated Microfluidic Chip Mimics Reciprocal Activation in Solid Tumor Microenvironment. PLoS One 11:e0159013 (2016). ICC/IF ; Human . PubMed: 27391808
  • Kefaloyianni E  et al. ADAM17 substrate release in proximal tubule drives kidney fibrosis. JCI Insight 1:N/A (2016). IF, IHC, WB ; Mouse . PubMed: 27642633
  • Sugiyama MG  et al. Influenza Virus Infection Induces Platelet-Endothelial Adhesion Which Contributes to Lung Injury. J Virol 90:1812-23 (2015). Human . PubMed: 26637453
  • Jiang C  et al. Tanshinone IIA Attenuates Renal Fibrosis after Acute Kidney Injury in a Mouse Model through Inhibition of Fibrocytes Recruitment. Biomed Res Int 2015:867140 (2015). Mouse . PubMed: 26885500
  • Al-Trad B  et al. Progesterone ameliorates diabetic nephropathy in streptozotocin-induced diabetic Rats. Diabetol Metab Syndr 7:97 (2015). IHC-P ; Rat . PubMed: 26583047
  • Morris EJ  et al. Integrin-linked kinase links dynactin-1/dynactin-2 with cortical integrin receptors to orient the mitotic spindle relative to the substratum. Sci Rep 5:8389 (2015). IHC-P ; Mouse . PubMed: 25669897
  • Nyström A  et al. Losartan ameliorates dystrophic epidermolysis bullosa and uncovers new disease mechanisms. EMBO Mol Med 7:1211-28 (2015). WB ; Human . PubMed: 26194911
  • Ravindran S  et al. Biomimetically enhanced demineralized bone matrix for bone regenerative applications. Front Physiol 6:292 (2015). IHC ; Mouse . PubMed: 26557093
  • Wang D  et al. Twist-related protein 1-mediated regulation of mesenchymal change contributes to the migration and invasion of cervical cancer cells. Oncol Lett 10:3107-3112 (2015). PubMed: 26722297
  • Taylor SH  et al. Matrix metalloproteinase 14 is required for fibrous tissue expansion. Elife 4:e09345 (2015). WB . PubMed: 26390284
  • Kolijn K  et al. Morphological and immunohistochemical identification of epithelial-to-mesenchymal transition in clinical prostate cancer. Oncotarget 6:24488-98 (2015). IF, IHC . PubMed: 26041890
  • Mo L  et al. Protective effect of Huang Gan formula in 5/6 nephrectomized rats by depressing the Wnt/ß-catenin signaling pathway. Drug Des Devel Ther 9:2867-81 (2015). PubMed: 26082617
  • Abdalla M  et al. Dasatinib inhibits TGFß-induced myofibroblast differentiation through Src-SRF Pathway. Eur J Pharmacol 769:134-42 (2015). PubMed: 26548624
  • Xiao L  et al. Tumor Endothelial Cells with Distinct Patterns of TGFß-Driven Endothelial-to-Mesenchymal Transition. Cancer Res 75:1244-54 (2015). PubMed: 25634211
  • Torr EE  et al. Myofibroblasts exhibit enhanced fibronectin assembly that is intrinsic to their contractile phenotype. J Biol Chem 290:6951-61 (2015). PubMed: 25627685
  • Turner DA  et al. Brachyury cooperates with Wnt/ß-catenin signalling to elicit primitive-streak-like behaviour in differentiating mouse embryonic stem cells. BMC Biol 12:63 (2014). PubMed: 25115237
  • Mirus JE  et al. Spatiotemporal proteomic analyses during pancreas cancer progression identifies serine/threonine stress kinase 4 (STK4) as a novel candidate biomarker for early stage disease. Mol Cell Proteomics 13:3484-96 (2014). PubMed: 25225358
  • Lu HJ  et al. Ruscogenin ameliorates diabetic nephropathy by its anti-inflammatory and anti-fibrotic effects in streptozotocin-induced diabetic rat. BMC Complement Altern Med 14:110 (2014). IHC . PubMed: 24666993
  • Gao J  et al. Emodin suppresses hyperglycemia-induced proliferation and fibronectin expression in mesangial cells via inhibiting cFLIP. PLoS One 9:e93588 (2014). WB . PubMed: 24691542
  • Chiyomaru T  et al. Long non-coding RNA HOTAIR is targeted and regulated by miR-141 in human cancer cells. J Biol Chem 289:12550-65 (2014). PubMed: 24616104
  • Hendel A  et al. Granzyme B releases vascular endothelial growth factor from extracellular matrix and induces vascular permeability. Lab Invest 94:716-25 (2014). PubMed: 24791744
  • Mu R  et al. Identification of a group B streptococcal fibronectin binding protein, SfbA, that contributes to invasion of brain endothelium and development of meningitis. Infect Immun 82:2276-86 (2014). Human . PubMed: 24643538
  • Marbiah MM  et al. Identification of a gene regulatory network associated with prion replication. EMBO J 33:1527-47 (2014). PubMed: 24843046
  • Bava FA  et al. CPEB1 coordinates alternative 3'-UTR formation with translational regulation. Nature 495:121-5 (2013). PubMed: 23434754
  • Morishita A  et al. HMGA2 is a driver of tumor metastasis. Cancer Res 73:4289-99 (2013). PubMed: 23722545
  • Gandavarapu NR  et al. Extracellular matrix protein adsorption to phosphate-functionalized gels from serum promotes osteogenic differentiation of human mesenchymal stem cells. Acta Biomater 9:4525-34 (2013). Human . PubMed: 22982322
  • Tzeng TF  et al. Zerumbone, a tropical ginger sesquiterpene, ameliorates streptozotocin-induced diabetic nephropathy in rats by reducing the hyperglycemia-induced inflammatory response. Nutr Metab (Lond) 10:64 (2013). WB . PubMed: 24499158
  • Küttner V  et al. Global remodelling of cellular microenvironment due to loss of collagen VII. Mol Syst Biol 9:657 (2013). IF . PubMed: 23591773
  • Arnold TD  et al. Deletion of integrin-linked kinase from neural crest cells in mice results in aortic aneurysms and embryonic lethality. Dis Model Mech 6:1205-12 (2013). PubMed: 23744273
  • Dai X  et al. Requirement for integrin-linked kinase in neural crest migration and differentiation and outflow tract morphogenesis. BMC Biol 11:107 (2013). IHC-P . PubMed: 24131868
  • Tang T  et al. Decreased body fat, elevated plasma transforming growth factor-ß levels, and impaired BMP4-like signaling in biglycan-deficient mice. Connect Tissue Res 54:5-13 (2013). PubMed: 22834985
  • Ashcroft KJ  et al. Site-specific keloid fibroblasts alter the behaviour of normal skin and normal scar fibroblasts through paracrine signalling. PLoS One 8:e75600 (2013). PubMed: 24348987
  • Marsden CG  et al. Disseminated breast cancer cells acquire a highly malignant and aggressive metastatic phenotype during metastatic latency in the bone. PLoS One 7:e47587 (2012). IHC . PubMed: 23173031
  • Grassian AR  et al. Isocitrate Dehydrogenase (IDH) Mutations Promote a Reversible ZEB1/MicroRNA (miR)-200-dependent Epithelial-Mesenchymal Transition (EMT). J Biol Chem 287:42180-94 (2012). PubMed: 23038259
  • Jin L  et al. Ubiquitin-dependent regulation of COPII coat size and function. Nature 482:495-500 (2012). PubMed: 22358839
  • Jiang J  et al. Overexpression of HTRA1 leads to down-regulation of fibronectin and functional changes in RF/6A cells and HUVECs. PLoS One 7:e46115 (2012). WB . PubMed: 23056244
  • Khoontawad J  et al. Proteomic Identification of Plasma Protein Tyrosine Phosphatase Alpha and Fibronectin Associated with Liver Fluke, Opisthorchis viverrini, Infection. PLoS One 7:e45460 (2012). WB, IHC . PubMed: 23029023
  • Syed F  et al. Keloid disease can be inhibited by antagonizing excessive mTOR signaling with a novel dual TORC1/2 inhibitor. Am J Pathol 181:1642-58 (2012). PubMed: 22982188
  • Kapinas K  et al. Bone matrix osteonectin limits prostate cancer cell growth and survival. Matrix Biol 31:299-307 (2012). PubMed: 22525512
  • Reticker-Flynn NE  et al. A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis. Nat Commun 3:1122 (2012). WB ; Mouse . PubMed: 23047680
  • Jaffe M  et al. Transforming growth factor-ß signaling in myogenic cells regulates vascular morphogenesis, differentiation, and matrix synthesis. Arterioscler Thromb Vasc Biol 32:e1-11 (2012). Mouse . PubMed: 21979435
  • Marsden CG  et al. "A novel in vivo model for the study of human breast cancer metastasis using primary breast tumor-initiating cells from patient biopsies". BMC Cancer 12:10 (2012). IHC-P ; Human . PubMed: 22233382
  • Worth DC  et al. Alpha v beta3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration. J Cell Biol 189:369-83 (2010). WB ; Mouse . PubMed: 20404115
  • Yen TH  et al. Proliferation of myofibroblasts in the stroma of renal oncocytoma. Cell Prolif : (2010). IHC-P ; Human . PubMed: 20412129
  • Bertocchi C  et al. Differential effects of NO inhibition in renal epithelial and endothelial cells in mono-culture vs. co-culture conditions. Cell Physiol Biochem 26:669-78 (2010). WB ; Human . PubMed: 21063104
  • Wolstein JM  et al. INK4a knockout mice exhibit increased fibrosis under normal conditions and in response to unilateral ureteral obstruction. Am J Physiol Renal Physiol 299:F1486-95 (2010). WB, IHC-P ; Mouse . PubMed: 20861074
  • Zhu WZ  et al. Neuregulin/ErbB signaling regulates cardiac subtype specification in differentiating human embryonic stem cells. Circ Res 107:776-86 (2010). PubMed: 20671236
  • Marrero B  et al. Generation of a tumor spheroid in a microgravity environment as a 3D model of melanoma. In Vitro Cell Dev Biol Anim 45:523-34 (2009). PubMed: 19533253
  • Bazigou E  et al. Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis. Dev Cell 17:175-86 (2009). WB ; Mouse . PubMed: 19686679
  • Solanas G  et al. E-cadherin controls beta-catenin and NF-kappaB transcriptional activity in mesenchymal gene expression. J Cell Sci 121:2224-34 (2008). WB ; Human . PubMed: 18565826

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