Overview

  • Product name
  • Description
    Rabbit polyclonal to Ficolin 2
  • Tested applications
    Suitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein, corresponding to amino acids 1-313 of Human Ficolin 2 (NP_004099.2).

  • Positive control
    • Human colon tissue lysate; Ficolin 2 transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab118374 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 34 kDa.
IP Use at an assay dependent dilution.

Target

  • Function
    May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region.
  • Tissue specificity
    Expressed by the liver and secreted in plasma.
  • Sequence similarities
    Belongs to the ficolin lectin family.
    Contains 1 collagen-like domain.
    Contains 1 fibrinogen C-terminal domain.
  • Domain
    The fibrinogen-like domain (FBG) contains potential calcium-binding sites that may be involved in carbohydrate binding.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • 37 kDa elastin-binding protein antibody
    • Collagen/fibrinogen domain containing protein 2 antibody
    • Collagen/fibrinogen domain-containing protein 2 antibody
    • EBP 37 antibody
    • EBP-37 antibody
    • EBP37 antibody
    • FCN 2 antibody
    • Fcn2 antibody
    • FCN2_HUMAN antibody
    • FCNL antibody
    • Ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) antibody
    • Ficolin B antibody
    • Ficolin beta antibody
    • Ficolin-2 antibody
    • Ficolin-B antibody
    • Ficolin-beta antibody
    • Ficolin2 antibody
    • Hucolin antibody
    • L ficolin antibody
    • L-ficolin antibody
    • OTTHUMP00000022518 antibody
    • P35 antibody
    • RP11 263F14.2 antibody
    • Serum lectin p35 antibody
    see all

Images

  • Anti-Ficolin 2 antibody (ab118374) at 1/1000 dilution + Human colon tissue lysate at 50 µg

    Predicted band size : 34 kDa
  • All lanes : Anti-Ficolin 2 antibody (ab118374) at 1/1000 dilution

    Lane 1 : Ficolin 2 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 34 kDa
  • Immunoprecipitation of Ficolin 2 transfected lysate using ab118374 and Protein A Magnetic Bead, and immunoblotted with anti-Ficolin 2 mouse polyclonal antibody.

References

ab118374 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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