The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000. Predicted molecular weight: 34 kDa.
Use at an assay dependent dilution.
FunctionMay function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region.
Tissue specificityExpressed by the liver and secreted in plasma.
Sequence similaritiesBelongs to the ficolin lectin family. Contains 1 collagen-like domain. Contains 1 fibrinogen C-terminal domain.
DomainThe fibrinogen-like domain (FBG) contains potential calcium-binding sites that may be involved in carbohydrate binding.