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Products:Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microfilaments >> Actin etc >> Actin Crosslinking
Overview
Product name
Anti-Filamin antibody [FLMN01 (PM6/317)]
See all Filamin products (2) ...
Description
Mouse monoclonal [FLMN01 (PM6/317)] to Filamin
Specificity
We don't have any information regarding the epitope location of the antigen therefore we do not know which isoform(s) is recognised by this antibody.
Tested applications
IHC-P, WBmore details
Cross reactivity
Reacts with
Rat, Human
Predicted to work with
Mouse, Rabbit, Chicken, Guinea pig
Immunogen
Platelet filamin.
Positive control
NIH3T3 cells. Skin tissue sections.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
10mM PBS, pH7.4, 0.2%BSA, 0.09% sodium azide
Concentration
Concentration information loading...
Purity
Protein G purified
Primary antibody notes
Filamin functions as a crosslinking protein forming a flexible link between two actin filaments. It is composed of two identical polypeptide chains each joined to the other at one end, with an actin binding site at the other. It is present in human platelets, lymphocytes, fibroblasts and smooth muscle actin.
Clonality
Monoclonal
Clone number
FLMN01 (PM6/317)
Isotype
IgG1
Research areas
Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microfilaments >> Actin etc >> Actin Binding Proteins
Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microfilaments >> Actin etc >> Actin Crosslinking
Applications
Show applications key
Our Abpromise guarantee covers the use of ab3261 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-P: Use a concentration of 1 - 2 µg/ml.Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
WB: Use a concentration of 1 - 2 µg/ml.Detects a band of approximately 250 kDa (predicted molecular weight: 280 kDa).
Target
Cellular localization
Cytoplasmic > cytoskeleton
Alternative names
- ABP 278 antibody
- ABP 280 antibody
- ABP 280 homolog antibody
see all
Database links
- Entrez Gene: 100722132 Guinea pig
- Entrez Gene: 100725162 Guinea pig
- Entrez Gene: 100730013 Guinea pig
- Entrez Gene: 2316 Human
- Entrez Gene: 2317 Human
- Entrez Gene: 2318 Human
- Entrez Gene: 100008760 Rabbit
- Entrez Gene: 100328754 Rabbit
see all
References for Anti-Filamin antibody [FLMN01 (PM6/317)] (ab3261)
This product has been referenced in:
- Jackson WMet al. Mechanical loading by fluid shear is sufficient to alter the cytoskeletal composition of osteoblastic cells. Am J Physiol Cell Physiol : (2008).Read more (PubMed: 18701650) »
See 1 publication for this product
Publishing research using ab3261? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"