Overview

  • Product name
    Anti-Filensin antibody
  • Description
    Rabbit polyclonal to Filensin
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant protein fragment corresponding to a region within amino acids 1-179 of Human Filensin (UniProt ID: Q12934).

  • Positive control
    • HCT116 whole cell lysate; U373 xenograft

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 0.75% Glycine, 1.21% Tris, 20% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab126235 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 75 kDa.
IHC-P 1/100 - 1/500. Suggested antigen retrieval: use heat mediated 10mM Citrate buffer(PH6.0) or Tris-EDTA buffer (PH 8.0).

Target

  • Tissue specificity
    Lens.
  • Involvement in disease
    Defects in BFSP1 are the cause of cataract cortical juvenile-onset (CCJO) [MIM:611391]. A juvenile-onset cataract with opacities restricted to the cortex of the lens, not involving the nucleus.
  • Sequence similarities
    Belongs to the intermediate filament family.
  • Cellular localization
    Membrane. Cytoplasm. Cytoplasm > cytoskeleton. Membrane- and cytoskeleton-associated.
  • Information by UniProt
  • Database links
  • Alternative names
    • Beaded filament structural protein 1 antibody
    • Beaded filament structural protein 1 filensin antibody
    • BFSP1 antibody
    • BFSP1_HUMAN antibody
    • CP115 antibody
    • CP94 antibody
    • CP95 antibody
    • Cytoskeletal protein, 115 KD antibody
    • Filensin antibody
    • Lens fiber cell beaded filament structural protein CP 115 antibody
    • Lens fiber cell beaded-filament structural protein CP 115 antibody
    • Lens intermediate filament like heavy antibody
    • Lens intermediate filament-like heavy antibody
    • LIFL H antibody
    • LIFL-H antibody
    see all

Images

  • Anti-Filensin antibody (ab126235) at 1/1000 dilution + HCT116 whole cell lysate at 30 µg

    Predicted band size : 75 kDa
  • ab126235, at a 1/500 dilution, staining Filensin in paraffin embedded U373 xenograft by Immunohistochemistry.

References

ab126235 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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