Overview

  • Product nameAnti-FILIP1L antibody
    See all FILIP1L primary antibodies
  • Description
    Rabbit polyclonal to FILIP1L
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    antigen sequence: DNEPPDYKSL IPLERAVING QLYEESENQD EDPNDEGSVL SFKCSQSTPC PVNRKLWIPW MKSKEGHLQN GKMQTKPNAN FVQPGDLVLS HTPGQP, corresponding to internal sequence amino acids 806-901 of Human FILIP1L.

  • Positive control
    • Human colon tissue; RT 4, U 251 MG, Liver and Tonsil lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab122835 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

Target

  • FunctionActs as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature.
  • Tissue specificityExpressed in endothelial cells, colon and colon cancers. In the colon, expressed in the vasculature and muscularis mucosa. In colon cancer, strongly expressed in tumor stroma and the vasculature (at protein level). Expressed in ovarian epithelial cells. Down-regulated in ovarian cancer.
  • Sequence similaritiesBelongs to the FILIP1 family.
  • Cellular localizationCytoplasm. Membrane. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 130 kDa GPBP-interacting protein antibody
    • 90 kDa GPBP-interacting protein antibody
    • COL4A3BPIP antibody
    • DOC-1 antibody
    • DOC1 antibody
    • Downregulated in ovarian cancer 1 81 kDa isoform antibody
    • FIL1L_HUMAN antibody
    • Filamin A-interacting protein 1-like antibody
    • FILIP1L antibody
    • GIP130 antibody
    • GIP130a antibody
    • GIP130b antibody
    • GIP130c antibody
    • GIP90 antibody
    • GPBP interacting protein 90 antibody
    • Protein down-regulated in ovarian cancer 1 antibody
    see all

Anti-FILIP1L antibody images

  • All lanes : Anti-FILIP1L antibody (ab122835) at 1/250 dilution

    Lane 1 : RT 4 lysate
    Lane 2 : U 251 MG lysate
    Lane 3 : Human Plasma lysate
    Lane 4 : Human liver lysate
    Lane 5 : Human tonsil lysate

    Developed using the ECL technique
  • ab122835 at 1/200 dilution staining FILIP1L in Paraffin-embedded Human colon tissue by Immunohistochemistry.

References for Anti-FILIP1L antibody (ab122835)

ab122835 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"