Overview

  • Product nameAnti-FKBP12 antibody [EP3887]
    See all FKBP12 primary antibodies
  • Description
    Rabbit monoclonal [EP3887] to FKBP12
  • Tested applicationsSuitable for: WB, ICC/IFmore details
    Unsuitable for: Flow Cyt,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) (internal sequence)

  • Positive control
    • HL-60, U937 and SH-SY5Y lysates; HeLa cells
  • General notes

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage bufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • PurityTissue culture supernatant
  • ClonalityMonoclonal
  • Clone numberEP3887
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab108420 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 12 kDa.
ICC/IF 1/50 - 1/100.
  • Application notesIs unsuitable for Flow Cyt,IHC-P or IP.
  • Target

    • FunctionMay play a role in modulation of ryanodine receptor isoform-1 (RYR-1), a component of the calcium release channel of skeletal muscle sarcoplasmic reticulum. There are four molecules of FKBP12 per skeletal muscle RYR. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
    • Sequence similaritiesBelongs to the FKBP-type PPIase family. FKBP1 subfamily.
      Contains 1 PPIase FKBP-type domain.
    • Cellular localizationCytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • 12 kDa FK506-binding protein antibody
      • 12 kDa FKBP antibody
      • Calstabin 1 antibody
      • FK506 binding protein 1 antibody
      • FK506 binding protein 12 antibody
      • FK506 binding protein 1A (12kD) antibody
      • FK506 binding protein 1A 12kDa antibody
      • FK506 binding protein 1A antibody
      • FK506 binding protein T cell 12 kD antibody
      • FK506 binding protein, T cell, 12 kD antibody
      • FK506 binding protein12 antibody
      • FK506-binding protein 1A antibody
      • FKB1A_HUMAN antibody
      • FKBP 12 antibody
      • FKBP 1A antibody
      • FKBP-12 antibody
      • FKBP-1A antibody
      • FKBP1 antibody
      • FKBP12 antibody
      • FKBP12 Exip3 antibody
      • FKBP12C antibody
      • fkbp1a antibody
      • Immunophilin FKBP12 antibody
      • Peptidyl prolyl cis trans isomerase antibody
      • Peptidyl-prolyl cis-trans isomerase FKBP1A antibody
      • PKC12 antibody
      • PKCI2 antibody
      • PPIase antibody
      • PPIase FKBP1A antibody
      • Protein kinase C inhibitor 2 antibody
      • Rotamase antibody
      see all

    Anti-FKBP12 antibody [EP3887] images

    • All lanes : Anti-FKBP12 antibody [EP3887] (ab108420) at 1/1000 dilution

      Lane 1 : Fetal brain lysate
      Lane 2 : HL-60 brain lysate
      Lane 3 : U937 lysate
      Lane 4 : SH-SY5Y lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 12 kDa
    • Immunofluorescent staining of FKBP12 in HeLa cells using ab108420 at 1/50 dilution.

    References for Anti-FKBP12 antibody [EP3887] (ab108420)

    ab108420 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab108420.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"