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Product name Anti-FKBP12 antibody [EP3887] See all FKBP12 primary antibodies
Rabbit monoclonal [EP3887] to FKBP12
Tested applications Suitable for:
WB, ICC/IF more details Unsuitable for:
Flow Cyt,IHC-P or IP
Mouse, Rat, Human
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) (internal sequence)
HL-60, U937 and SH-SY5Y lysates; HeLa cells
Produced using Abcam’s RabMAb
® technology. RabMAb ® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.
Storage instructions Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage buffer PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purity Tissue culture supernatant
Clone number EP3887
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000 - 1/10000. Predicted molecular weight: 12 kDa.
1/50 - 1/100.
Application notes Is unsuitable for Flow Cyt,IHC-P or IP.
Function May play a role in modulation of ryanodine receptor isoform-1 (RYR-1), a component of the calcium release channel of skeletal muscle sarcoplasmic reticulum. There are four molecules of FKBP12 per skeletal muscle RYR. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Sequence similarities Belongs to the FKBP-type PPIase family. FKBP1 subfamily. Contains 1 PPIase FKBP-type domain.
Cellular localization Cytoplasm.
Information by UniProt
12 kDa FK506-binding protein antibody
12 kDa FKBP antibody
Calstabin 1 antibody
Anti-FKBP12 antibody [EP3887] images
Western blot - FKBP12 antibody [EP3887] (ab108420)
All lanes : Anti-FKBP12 antibody [EP3887] (ab108420) at 1/1000 dilution Lane 1 : Fetal brain lysate Lane 2 : HL-60 brain lysate Lane 3 : U937 lysate Lane 4 : SH-SY5Y lysate Lysates/proteins at 10 µg per lane. Secondary HRP labelled goat anti-rabbit at 1/2000 dilution Predicted band size : 12 kDa
Immunocytochemistry/ Immunofluorescence - FKBP12 antibody [EP3887] (ab108420)
Immunofluorescent staining of FKBP12 in HeLa cells using ab108420 at 1/50 dilution.
References for Anti-FKBP12 antibody [EP3887] (ab108420)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"