Overview

Description

  • Nature
    Synthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab4924 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Additional notes


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human FKBP 51, catalog ab2901. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

General Info

  • Alternative names
    • 51 kDa FK506 binding protein
    • 51 kDa FK506 binding protein 5
    • 51 kDa FK506-binding protein
    • 51 kDa FKBP
    • 54 kDa progesterone receptor associated immunophilin
    • 54 kDa progesterone receptor-associated immunophilin
    • AIG 6
    • AIG6
    • Androgen regulated protein 6
    • Androgen-regulated protein 6
    • FF1 antigen
    • FK506 binding protein 5
    • FK506-binding protein 5
    • FKBP 5
    • FKBP 51
    • FKBP 54
    • FKBP-5
    • FKBP-51
    • FKBP5
    • FKBP5_HUMAN
    • FKBP54
    • HSP90 binding immunophilin
    • HSP90-binding immunophilin
    • MGC111006
    • OTTHUMP00000016268
    • P54
    • Peptidyl prolyl cis trans isomerase
    • Peptidyl-prolyl cis-trans isomerase FKBP5
    • Peptidylprolyl cis trans isomerase
    • PPIase
    • PPIase FKBP5
    • Ptg 10
    • Ptg10
    • Rotamase
    • T cell FK506 binding protein
    see all
  • Function
    Interacts with functionally mature heterooligomeric progesterone receptor complexes along with HSP90 and TEBP.
  • Tissue specificity
    Widely expressed, enriched in testis compared to other tissues.
  • Sequence similarities
    Contains 2 PPIase FKBP-type domains.
    Contains 3 TPR repeats.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt

References

ab4924 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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