Recombinant
RabMAb

Anti-FKBP6 antibody [EPR3674] (ab92475)

Overview

  • Product name
    Anti-FKBP6 antibody [EPR3674]
    See all FKBP6 primary antibodies
  • Description
    Rabbit monoclonal [EPR3674] to FKBP6
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-P, Flow Cytmore details
    Unsuitable for: ICC/IF or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human FKBP6 aa 250-350 (C terminal). The exact sequence is proprietary.

  • Positive control
    • Molt-4 and SAOS-2 cell lysates. Human tonsil tissue.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer
    PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • Purity
    Tissue culture supernatant
  • Clonality
    Monoclonal
  • Clone number
    EPR3674
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab92475 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-P
Flow Cyt
  • Application notes
    Flow Cyt: 1/10 - 1/100.
    IHC-P: 1/100 - 1/250 antigen retrieval is recommended.
    WB: 1/1000 - 1/10000. Detects a band of approximately 38 kDa (predicted molecular weight: 37 kDa).

    Is unsuitable for ICC/IF or IP.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      PPIases accelerate the folding of proteins.
    • Tissue specificity
      Detected in all tissues examined, with higher expression in testis, heart, skeletal muscle, liver, and kidney.
    • Involvement in disease
      Note=FKBP6 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of FKBP6 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
    • Sequence similarities
      Contains 1 PPIase FKBP-type domain.
      Contains 3 TPR repeats.
    • Information by UniProt
    • Database links
    • Alternative names
      • 36 kDa FK506 binding protein antibody
      • 36 kDa FK506-binding protein antibody
      • 36 kDa FKBP antibody
      • EC 5.2.1.8 antibody
      • FK506 binding protein 6 antibody
      • FK506-binding protein 6 antibody
      • FKBP 36 antibody
      • FKBP-36 antibody
      • FKBP-6 antibody
      • FKBP36 antibody
      • fkbp6 antibody
      • FKBP6_HUMAN antibody
      • Immunophilin FKBP36 antibody
      • Peptidyl prolyl cis trans isomerase antibody
      • Peptidyl-prolyl cis-trans isomerase FKBP6 antibody
      • PPIase antibody
      • PPIase FKBP6 antibody
      • Rotamase antibody
      see all

    Images

    • All lanes : Anti-FKBP6 antibody [EPR3674] (ab92475) at 1/1000 dilution

      Lane 1 : Molt-4 cell lysate
      Lane 2 : SAOS-2 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled goat anti-rabbit antibody at 1/2000 dilution

      Predicted band size: 37 kDa
      Observed band size: 38 kDa (why is the actual band size different from the predicted?)

    • Ab92475 at 1/100 dilution staining FKBP6 in paraffin-embedded Human tonsil tissue, by immunohistochemistry.

    References

    ab92475 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab92475.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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