• Product nameAnti-FKLF / KLF11 antibody
    See all FKLF / KLF11 primary antibodies
  • Description
    Rabbit polyclonal to FKLF / KLF11
  • Specificityab65029 detects endogenous levels of total FKLF / KLF11 protein.
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide derived from an internal sequence of human FKLF/ KLF11

  • Positive control
    • 293, Jurkat and HuvEc cell extracts.



Our Abpromise guarantee covers the use of ab65029 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/20000.
WB 1/500 - 1/1000. Detects a band of approximately 56 kDa (predicted molecular weight: 56 kDa).


  • FunctionTranscription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis.
  • Tissue specificityUbiquitous. Higher expression in erythroid cells.
  • Involvement in diseaseDefects in KLF11 are the cause of maturity-onset diabetes of the young type 7 (MODY7) [MIM:610508]. MODY is a form of diabetes that is characterized by an autosomal dominant mode of inheritance, onset in childhood or early adulthood (usually before 25 years of age), a primary defect in insulin secretion and frequent insulin-independence at the beginning of the disease.
  • Sequence similaritiesBelongs to the Sp1 C2H2-type zinc-finger protein family.
    Contains 3 C2H2-type zinc fingers.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 9830142A17 antibody
    • D12Ertd427e antibody
    • FKLF antibody
    • FKLF1 antibody
    • Klf11 antibody
    • KLF11_HUMAN antibody
    • Krueppel like factor 11 antibody
    • Krueppel-like factor 11 antibody
    • MODY7 antibody
    • Tcfcp2l2 antibody
    • TGFB Early Growth Response 2 antibody
    • TGFB-inducible early growth response protein 2 antibody
    • TGFB-inducible early growth response protein 2b antibody
    • TGFB-inducible early growth response protein 3 antibody
    • TIEG 2 antibody
    • TIEG-2 antibody
    • TIEG-3 antibody
    • Tieg2b antibody
    • Transforming Growth Factor Beta Inducible Early Growth Response 2 antibody
    • Transforming growth factor-beta-inducible early growth response protein 2 antibody
    • Transforming growth factor-beta-inducible early growth response protein 3 antibody
    see all

Anti-FKLF / KLF11 antibody images

  • All lanes : Anti-FKLF / KLF11 antibody (ab65029) at 1/500 dilution

    Lane 1 : 293 cell extract
    Lane 2 : Jurkat cell extract
    Lane 3 : HuvEc cell extract
    Lane 4 : HuvEc cell extract with immunising peptide at 10 µg

    Lysates/proteins at 5 µg per lane.

    Predicted band size : 56 kDa
    Observed band size : 56 kDa

References for Anti-FKLF / KLF11 antibody (ab65029)

This product has been referenced in:
  • Jung CJ  et al. Human ESC Self-renewal Promoting microRNAs Induce Epithelial-Mesenchymal Transition in Hepatocytes by Controlling the PTEN and TGFß Tumor Suppressor Signaling Pathways. Mol Cancer Res 10:979-91 (2012). WB ; Human . Read more (PubMed: 22622027) »

See 1 Publication for this product

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