• Product nameAnti-FLASH antibody
    See all FLASH primary antibodies
  • Description
    Rabbit polyclonal to FLASH
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide, corresponding to a region between residues 1650 and 1700 of human FLASH (NP_036247.1)

  • Positive control
    • Human controls: Breast Carcinoma, Ovarian Carcinoma, Prostate Carcinoma, Small Cell Lung Cancer tissues. Mouse controls: Colon Carcinoma, CT26, Teratoma tissues.
  • General notesAntibody concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG. Centrifuge microtube to remove product from lid.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab84748 was affinity purified using an epitope specific to FLASH immobilized on solid support.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab84748 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesIHC-P: 1/100 - 1/500.
    Epitope exposure with citrate buffer will enhance staining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionParticipates in TNF-alpha-induced blockade of glucocorticoid receptor (GR) transactivation at the nuclear receptor coactivator level, upstream and independently of NF-kappa-B. Suppresses both NCOA2- and NCOA3-induced enhancement of GR transactivation. Involved in TNF-alpha-induced activation of NF-kappa-B via a TRAF2-dependent pathway. Acts as a downstream mediator for CASP8-induced activation of NF-kappa-B. Required for the activation of CASP8 in FAS-mediated apoptosis. Required for histone gene transcription and progression through S phase.
    • Post-translational
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localizationCytoplasm. Nucleus. Localizes to discrete nuclear foci.
    • Information by UniProt
    • Database links
    • Alternative names
      • AA387232 antibody
      • C8AP2_HUMAN antibody
      • CASP 8 associated protein 2 antibody
      • CASP8 associated protein 2 antibody
      • CASP8-associated protein 2 antibody
      • CASP8AP2 antibody
      • Caspase 8 associated protein 2 antibody
      • CED 4 antibody
      • CED4 antibody
      • D4Ertd659e antibody
      • FLASH homolog antibody
      • FLASH homolog RIP 25 antibody
      • FLASH homolog RIP25 antibody
      • FLICE associated huge antibody
      • FLICE associated huge protein antibody
      • FLICE-associated huge protein antibody
      • FLJ11208 antibody
      • KIAA1315 antibody
      • mKIAA1315 antibody
      • OTTMUSP00000005125 antibody
      • RIP 25 antibody
      • RIP25 antibody
      • RP23-69G24.1 antibody
      see all

    Anti-FLASH antibody images

    • ab84748 at 1/250 dilution staining FLASH in human prostate nodular hypertrophy by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.
    • ab84748 at 1/250 dilution staining FLASH in mouse teratoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.

    References for Anti-FLASH antibody (ab84748)

    ab84748 has not yet been referenced specifically in any publications.

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