Overview

  • Product nameAnti-FLJ39378 antibody
    See all FLJ39378 primary antibodies
  • Description
    Rabbit polyclonal to FLJ39378
  • Tested applicationsSuitable for: ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    17 amino acid synthetic peptide derived from near the N terminal of Human FLJ39378 (AAH89444).

  • Positive control
    • Rat cerebellum tissue lysate.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab117441 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 47 kDa.

Target

  • FunctionNeuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution.
  • Tissue specificityWidely expressed. Expressed at lower level in liver and kidney.
  • Sequence similaritiesBelongs to the RILPL family.
    Contains 1 RILP-like domain.
  • Post-translational
    modifications
    S-nitrosylation is required for the interaction with GAPDH.
  • Cellular localizationCytoplasm > cytosol.
  • Information by UniProt
  • Database links
  • Alternative names
    • GOSPEL antibody
    • MGC105128 antibody
    • MGC99793 antibody
    • Rab interacting lysosomal protein like 1 antibody
    • Rab-interacting lysosomal-like protein 1 antibody
    • RILP like protein 1 antibody
    • RILP-like protein 1 antibody
    • RILPL 1 antibody
    • rilpl1 antibody
    • RIPL1_HUMAN antibody
    • RLP1 antibody
    see all

Anti-FLJ39378 antibody images

  • Lane 1 : Anti-FLJ39378 antibody (ab117441) at 0.5 µg/ml
    Lane 2 : Anti-FLJ39378 antibody (ab117441) at 1 µg/ml

    Lane 1 : Rat cerebellum tissue lysate
    Lane 2 : Rat cerebellum tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 47 kDa
  • Immunofluorescence analysis of mouse brain cells, staining FLJ39378 with ab117441 at 20 µg/ml.

References for Anti-FLJ39378 antibody (ab117441)

ab117441 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"