Overview

  • Product nameAnti-Flotillin 2 antibody
    See all Flotillin 2 primary antibodies
  • Description
    Rabbit polyclonal to Flotillin 2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide:

    IKKAT

    , corresponding to a region around amino acids 420-424 of Human Esa1 (Q14254).

  • Positive control
    • JK, HUVEC, HepG2 and HeLa cell extracts

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab123376 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 47 kDa (predicted molecular weight: 47 kDa). Incubate membrane with diluted antibody in 5% nonfat milk, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking over night.

Target

  • FunctionMay act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.
  • Tissue specificityIn skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carcinoma cell lines, fibroblasts and foreskin melanocytes.
  • Sequence similaritiesBelongs to the band 7/mec-2 family. Flotillin subfamily.
  • Cellular localizationCell membrane. Membrane > caveola. Endosome. Membrane-associated protein of caveolae.
  • Information by UniProt
  • Database links
  • Alternative names
    • ECS-1 antibody
    • ECS1 antibody
    • Epidermal surface antigen 1 antibody
    • Epidermal surface antigen antibody
    • ESA antibody
    • ESA1 antibody
    • Flot2 antibody
    • FLOT2_HUMAN antibody
    • Flotillin 2 (epidermal surface antigen 1) antibody
    • Flotillin-2 antibody
    • M17S1 antibody
    • Membrane component chromosome 17 surface marker 1 antibody
    • Membrane component chromosome 17 surface marker 1 homolog antibody
    • membrane component, chromosome 17, surface marker 1 (35kD protein identified by monoclonal antibody ECS-1) antibody
    • Membrane component, chromosome 17, surface marker 1 antibody
    • REG-1 antibody
    • Reggie-1 antibody
    • Reggie-2 antibody
    see all

Anti-Flotillin 2 antibody images

  • All lanes : Anti-Flotillin 2 antibody (ab123376) at 1/500 dilution

    Lane 1 : JK cell extract
    Lane 2 : HUVEC cell extract
    Lane 3 : HepG2 cell extract
    Lane 4 : HeLa cell extract


    Predicted band size : 47 kDa

References for Anti-Flotillin 2 antibody (ab123376)

ab123376 has not yet been referenced specifically in any publications.

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