Recombinant
RabMAb

Anti-Flt3 / CD135 (phospho Y589) antibody [EPR2311(2)] (ab171975)

Overview

  • Product name
    Anti-Flt3 / CD135 (phospho Y589) antibody [EPR2311(2)]
    See all Flt3 / CD135 primary antibodies
  • Description
    Rabbit monoclonal [EPR2311(2)] to Flt3 / CD135 (phospho Y589)
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ICC/IFmore details
    Unsuitable for: Flow Cyt,IHC-P or IP
  • Species reactivity
    Reacts with: Human
    Does not react with: Mouse, Rat
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human Flt3/ CD135 aa 550-650 (phospho Y589) (Cysteine residue). The exact sequence is proprietary.
    Database link: P36888

  • Positive control
    • A431 cell lysate.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab171975 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Detects a band of approximately 130-160 kDa (predicted molecular weight: 112 kDa).
ICC/IF 1/100 - 1/250.
  • Application notes
    Is unsuitable for Flow Cyt,IHC-P or IP.
  • Target

    • Function
      Receptor for the FL cytokine. Has a tyrosine-protein kinase activity.
    • Tissue specificity
      Bone marrow cells.
    • Sequence similarities
      Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
      Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
      Contains 1 protein kinase domain.
    • Cellular localization
      Membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD 135 antibody
      • CD135 antibody
      • CD135 antigen antibody
      • Fetal liver kinase 2 antibody
      • FL cytokine receptor antibody
      • Flk 2 antibody
      • Flk2 antibody
      • Flt 3 antibody
      • FLT-3 antibody
      • Flt3 antibody
      • FLT3_HUMAN antibody
      • FMS like tyrosine kinase 3 antibody
      • Fms related tyrosine kinase 3 antibody
      • Fms-like tyrosine kinase 3 antibody
      • Growth factor receptor tyrosine kinase type III antibody
      • Ly-72 antibody
      • OTTHUMP0000004234 antibody
      • Receptor type tyrosine protein kinase FLT3 antibody
      • Stem cell tyrosine kinase 1 antibody
      • Stk 1 antibody
      • STK-1 antibody
      • Stk1 antibody
      • Tyrosine protein kinase receptor FLT3 antibody
      • Tyrosine-protein kinase receptor FLT3 antibody
      see all

    Images

    • All lanes : Anti-Flt3 / CD135 (phospho Y589) antibody [EPR2311(2)] (ab171975) at 1/1000 dilution

      Lane 1 : A431 cell lysate - untreated
      Lane 2 : A431 cell lysate - treated with pervanadate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 112 kDa

    References

    This product has been referenced in:
    • Kang CW  et al. Antitumor Activity and Acquired Resistance Mechanism of Dovitinib (TKI258) in RET-Rearranged Lung Adenocarcinoma. Mol Cancer Ther 14:2238-48 (2015). Read more (PubMed: 26208525) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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