Anti-FMNL2 antibody (ab72105)
Key features and details
- Rabbit polyclonal to FMNL2
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-FMNL2 antibody
See all FMNL2 primary antibodies -
Description
Rabbit polyclonal to FMNL2 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Cow -
Immunogen
Synthetic peptide corresponding to Human FMNL2 (N terminal).
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Positive control
- Mouse embryo body tissue lysate; Paraffin embedded Human brain tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 0.05% BSA, PBS -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab72105 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 123 kDa (predicted molecular weight: 123 kDa).
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IHC-P |
Use a concentration of 5 - 10 µg/ml.
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Notes |
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WB
Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 123 kDa (predicted molecular weight: 123 kDa). |
IHC-P
Use a concentration of 5 - 10 µg/ml. |
Target
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Relevance
This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has yet to be determined. -
Cellular localization
Cytoplasm -
Database links
- Entrez Gene: 114793 Human
- Entrez Gene: 71409 Mouse
- Omim: 616285 Human
- SwissProt: Q96PY5 Human
- SwissProt: A2APV2 Mouse
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Alternative names
- FHOD2 antibody
- Formin homology 2 domain containing protein 2 antibody
- Formin like 2 antibody
see all
Images
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All lanes : Anti-FMNL2 antibody (ab72105) at 2 µg/ml
Lane 1 : mouse embryo body tissue lysate
Lane 2 : mouse embryo body tissue lysate with immunizing peptide
Predicted band size: 123 kDa
Observed band size: 123 kDa
Additional bands at: 40 kDa. We are unsure as to the identity of these extra bands. -
Immunohistochemical analysis of FMNL2 expression in paraffin embedded human brain cortical tissue using ab72105 at 10ug/ml.
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Immunohistochemical analysis of FMNL2 expression in paraffin embedded normal human brain tissue using ab72105 at 6 ug/ml (figure A) and a control rabbit Ig (figure B).
Protocols
Datasheets and documents
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Datasheet download
References (4)
ab72105 has been referenced in 4 publications.
- Lee SW et al. Formin-Like 2 Is a Potential Biomarker of Poor Prognosis in Nasopharyngeal Carcinoma. Oncology 100:475-484 (2022). PubMed: 35772391
- Guo J et al. Expression of Formin-like 2 and cortactin in gallbladder adenocarcinoma and their clinical significance. Int J Clin Exp Pathol 13:1655-1661 (2020). PubMed: 32782685
- Monzo P et al. Mechanical confinement triggers glioma linear migration dependent on formin FHOD3. Mol Biol Cell 27:1246-61 (2016). Rat . PubMed: 26912794
- Panzer L et al. The formins FHOD1 and INF2 regulate inter- and intra-structural contractility of podosomes. J Cell Sci 129:298-313 (2016). WB ; Human . PubMed: 26621033