Overview

  • Product name
  • Description
    Rabbit polyclonal to FMNL2
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Rat, Human, Chimpanzee, Monkey
    Predicted to work with: Mouse, Cow
  • Immunogen

    Synthetic peptide corresponding to Human FMNL2 (N terminal).

  • Positive control
    • Mouse embryo body tissue lysate; Paraffin embedded Human brain tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.05% Sodium Azide
    Constituents: 0.05% BSA, PBS
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab72105 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 123 kDa (predicted molecular weight: 123 kDa).
IHC-P Use a concentration of 5 - 10 µg/ml.

Target

  • Relevance
    This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has yet to be determined.
  • Cellular localization
    Cytoplasm
  • Database links
  • Alternative names
    • FHOD2 antibody
    • Formin homology 2 domain containing protein 2 antibody
    • Formin like 2 antibody
    • Formin like protein 2 antibody
    • KIAA1902 antibody
    see all

Images

  • All lanes : Anti-FMNL2 antibody (ab72105) at 2 µg/ml

    Lane 1 : mouse embryo body tissue lysate
    Lane 2 : mouse embryo body tissue lysate with immunizing peptide


    Predicted band size : 123 kDa
    Observed band size : 123 kDa
    Additional bands at : 40 kDa. We are unsure as to the identity of these extra bands.
  • Immunohistochemical analysis of FMNL2 expression in paraffin embedded human brain cortical tissue using ab72105 at 10ug/ml.
  • Immunohistochemical analysis of FMNL2 expression in paraffin embedded normal human brain tissue using ab72105 at 6 ug/ml (figure A) and a control rabbit Ig (figure B).

References

This product has been referenced in:
  • Monzo P  et al. Mechanical confinement triggers glioma linear migration dependent on formin FHOD3. Mol Biol Cell 27:1246-61 (2016). Rat . Read more (PubMed: 26912794) »
  • Panzer L  et al. The formins FHOD1 and INF2 regulate inter- and intra-structural contractility of podosomes. J Cell Sci 129:298-313 (2016). WB ; Human . Read more (PubMed: 26621033) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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