Overview

  • Product name
    Anti-FMO2 antibody
  • Description
    Rabbit polyclonal to FMO2
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Monkey
  • Immunogen

    Recombinant fragment containing a sequence corresponding to a region within amino acids 74-324 of Human FMO2 (NP_001451).

  • Positive control
    • HepG2 whole cell lysate; A549 xenograft; 293T, A431, H1299, HeLa, Molt4 and Raji lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab95977 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 61 kDa.
IHC-P 1/100 - 1/500.

Target

  • Function
    Catalyzes the N-oxidation of certain primary alkylamines to their oximes via an N-hydroxylamine intermediate. Inactive toward certain tertiary amines, such as imipramine or chloropromazine. Can catalyze the S-oxidation of methimazole. The truncated form is catalytically inactive.
  • Tissue specificity
    Expressed in lung (at protein level). Expressed predominantly in lung, and at a much lesser extent in kidney. Also expressed in fetal lung, but not in liver, kidney and brain.
  • Sequence similarities
    Belongs to the FMO family.
  • Post-translational
    modifications
    The truncated form is probably unable to fold correctly and is rapidly degraded.
    FMO2*1 is sumoylated at 'Lys-492'.
  • Cellular localization
    Microsome membrane. Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2310008D08Rik antibody
    • 2310042I22Rik antibody
    • AW107733 antibody
    • Dimethylaniline monooxygenase [N oxide forming] 2 antibody
    • Dimethylaniline monooxygenase [N-oxide-forming] 2 antibody
    • Dimethylaniline oxidase 2 antibody
    • Flavin containing monooxygenase 2 (non functional) antibody
    • Flavin containing monooxygenase 2 antibody
    • FLJ40826 antibody
    • FMO 1B1 antibody
    • FMO 2 antibody
    • FMO antibody
    • FMO pulmonary antibody
    • FMO1B1 antibody
    • FMO2 antibody
    • FMO2_HUMAN antibody
    • MGC28212 antibody
    • OTTMUSP00000028686 antibody
    • OTTMUSP00000028687 antibody
    • Pulmonary flavin containing monooxygenase 2 antibody
    • Pulmonary flavin-containing monooxygenase 2 antibody
    see all

Images

  • Anti-FMO2 antibody (ab95977) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 61 kDa
  • ab95977, at 1/500 dilution, staining FMO2 in paraffin-embedded A549 xenograft by Immunohistochemistry.

References

ab95977 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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