Overview

  • Product nameAnti-FMO3 antibody
    See all FMO3 primary antibodies
  • Description
    Mouse polyclonal to FMO3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length Human FMO3 protein (AAH32016.1)

  • Positive control
    • Human liver tissue lysate, FMO3 transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab92902 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/500 - 1/1000. Predicted molecular weight: 60 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionInvolved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. It N-oxygenates primary aliphatic alkylamines as well as secondary and tertiary amines. Plays an important role in the metabolism of trimethylamine (TMA), via the production of TMA N-oxide (TMAO). Is also able to perform S-oxidation when acting on sulfide compounds.
    • Tissue specificityLiver.
    • Involvement in diseaseDefects in FMO3 are the cause of trimethylaminuria (TMAU) [MIM:602079]; also known as fish-odor syndrome. TMAU is an inborn error of metabolism associated with an offensive body odor and caused by deficiency of FMO-mediated N-oxidation of amino-trimethylamine (TMA) derived from foodstuffs. Such individuals excrete relatively large amounts of TMA in their urine, sweat, and breath, and exhibit a fishy body odor characteristic of the malodorous free amine.
    • Sequence similaritiesBelongs to the FMO family.
    • Cellular localizationMicrosome membrane. Endoplasmic reticulum membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Dimethylaniline monooxygenase [N oxide forming] 3 antibody
      • Dimethylaniline monooxygenase [N-oxide-forming] 3 antibody
      • Dimethylaniline monooxygenase 3 antibody
      • Dimethylaniline oxidase 3 antibody
      • dJ127D3.1 antibody
      • Flavin containing monooxygenase 3 antibody
      • FMO 3 antibody
      • FMO form 2 antibody
      • FMO II antibody
      • FMO3 antibody
      • FMO3_HUMAN antibody
      • FMOII antibody
      • Hepatic flavin containing monooxygenase 3 antibody
      • Hepatic flavin-containing monooxygenase 3 antibody
      • MGC34400 antibody
      • TMAU antibody
      • Trimethylamine monooxygenase antibody
      see all

    Anti-FMO3 antibody images

    • Anti-FMO3 antibody (ab92902) at 1/500 dilution + Human liver tissue lysate at 50 µg

      Predicted band size : 60 kDa
    • All lanes : Anti-FMO3 antibody (ab92902) at 1/500 dilution

      Lane 1 : FMO3 transfected 293T cell lysate
      Lane 2 : Untransfected 293T cell lysate

      Lysates/proteins at 25 µg per lane.


      Predicted band size : 60 kDa
      Observed band size : 59 kDa (why is the actual band size different from the predicted?)

    References for Anti-FMO3 antibody (ab92902)

    ab92902 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab92902.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"