Overview

  • Product nameAnti-FMRFamide antibody
    See all FMRFamide primary antibodies
  • Description
    Rabbit polyclonal to FMRFamide
  • Tested applicationsIHC-Fr, IHC, ICC/IFmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    Synthetic peptide:

    FMRF-NH2

    .

  • General notes


    Phe Met Arg Phe-NH2, a tetrapeptide neurotransmitter, a member of the same family of RFamide peptides as FLRFamide, sharing the same C terminal RFamide sequence. FMFRamide-related protein precursor plays a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. FMRFAL Gene encodes a preproprotein where upon cleavage forms two active peptides possessing similar function.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.05% Sodium Azide
    Constituents: Whole Serum
  • PurityWhole antiserum
  • Primary antibody notes Phe Met Arg Phe-NH2, a tetrapeptide neurotransmitter, a member of the same family of RFamide peptides as FLRFamide, sharing the same C terminal RFamide sequence. FMFRamide-related protein precursor plays a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. FMRFAL Gene encodes a preproprotein where upon cleavage forms two active peptides possessing similar function.
  • Clonality Polyclonal
  • IsotypeIgG
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab10352 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr 1/1000 - 1/5000.
IHC Use at an assay dependent concentration. ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
ICC/IF Use at an assay dependent concentration.

Target

  • RelevanceFMRFamide related peptides are morphine modulating peptides that have many physiologic effects, including the modulation of morphine induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas. Neuropeptide FF potentiates and sensitizes ACCN2 and ACCN3 channels.
  • Cellular localizationSecreted
  • Database links
  • Alternative names
    • FMFRamide related peptide precursor antibody
    • FMRFAL antibody
    • FMRFamide related peptides precursor antibody
    • FMRFamide-related peptides [Precursor] antibody
    • Neuropeptide FF amide peptide precursor antibody
    • NPFF antibody
    • NPFF protein antibody
    see all

Anti-FMRFamide antibody images

  • ab10352 staining FMRFamide in rat spinal cord by Immunohistochemistry (PFA perfusion fixed frozen sections).

References for Anti-FMRFamide antibody (ab10352)

This product has been referenced in:
  • Jager M  et al. Multiple Sox genes are expressed in stem cells or in differentiating neuro-sensory cells in the hydrozoan Clytia hemisphaerica. Evodevo 2:12 (2011). ICC/IF . Read more (PubMed: 21631916) »
  • Chiori R  et al. Are Hox genes ancestrally involved in axial patterning? Evidence from the hydrozoan Clytia hemisphaerica (Cnidaria). PLoS ONE 4:e4231 (2009). IHC-Fr . Read more (PubMed: 19156208) »

See all 2 Publications for this product

Product Wall

Application Immunocytochemistry/ Immunofluorescence
Sample Rabbit Cell (whole animal = microscopic rotifer (nerve tissue))
Specification whole animal = microscopic rotifer (nerve tissue)
Fixative Paraformaldehyde
Permeabilization Yes - 0.5% Triton X-100
Username

Dr. R Hochberg

Verified customer

Submitted Jan 23 2008

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"