Overview

  • Product name
  • Description
    Rabbit polyclonal to FMRFamide
  • Tested applications
    Suitable for: IHC-Fr, ICC/IFmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    Synthetic peptide:

    FMRF-NH2

    .

  • General notes


    Phe Met Arg Phe-NH2, a tetrapeptide neurotransmitter, a member of the same family of RFamide peptides as FLRFamide, sharing the same C terminal RFamide sequence. FMFRamide-related protein precursor plays a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. FMRFAL Gene encodes a preproprotein where upon cleavage forms two active peptides possessing similar function.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.05% Sodium Azide
    Constituents: Whole Serum
  • Purity
    Whole antiserum
  • Primary antibody notes
    Phe Met Arg Phe-NH2, a tetrapeptide neurotransmitter, a member of the same family of RFamide peptides as FLRFamide, sharing the same C terminal RFamide sequence. FMFRamide-related protein precursor plays a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. FMRFAL Gene encodes a preproprotein where upon cleavage forms two active peptides possessing similar function.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab10352 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr 1/1000 - 1/5000.
ICC/IF Use at an assay dependent concentration.

Target

  • Relevance
    FMRFamide related peptides are morphine modulating peptides that have many physiologic effects, including the modulation of morphine induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas. Neuropeptide FF potentiates and sensitizes ACCN2 and ACCN3 channels.
  • Cellular localization
    Secreted
  • Database links
  • Alternative names
    • FMFRamide related peptide precursor antibody
    • FMRFAL antibody
    • FMRFamide related peptides precursor antibody
    • Neuropeptide FF amide peptide precursor antibody
    • NPFF antibody
    • NPFF protein antibody
    see all

Anti-FMRFamide antibody images

  • ab10352 staining FMRFamide in rat spinal cord by Immunohistochemistry (PFA perfusion fixed frozen sections).

References for Anti-FMRFamide antibody (ab10352)

This product has been referenced in:
  • von Döhren J Development of the Nervous System of Carinina ochracea (Palaeonemer-tea, Nemertea). PLoS One 11:e0165649 (2016). IHC, ICC/IF . Read more (PubMed: 27792762) »
  • Burbach JP  et al. Differential expression of the FMRF gene in adult and hatchling stellate ganglia of the squid Loligo pealei. Biol Open 3:50-8 (2014). IHC . Read more (PubMed: 24326188) »

See all 4 Publications for this product

Product Wall

Application
Immunocytochemistry/ Immunofluorescence
Sample
Rabbit Cell (whole animal = microscopic rotifer (nerve tissue))
Specification
whole animal = microscopic rotifer (nerve tissue)
Fixative
Paraformaldehyde
Permeabilization
Yes - 0.5% Triton X-100
Username

Dr. R Hochberg

Verified customer

Submitted Jan 23 2008

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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