Overview

  • Product nameAnti-FNBP1L antibody
    See all FNBP1L primary antibodies
  • Description
    Rabbit polyclonal to FNBP1L
  • Tested applicationsSuitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Platypus (Ornithorhynchus anatinus), Elephant
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 50-100 of Human FNBP1L (NP_001157945.1).

  • Positive control
    • Jurkat whole cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab124277 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-10 µg/mg of lysate.
  • Application notesIs unsuitable for WB.
  • Target

    • FunctionRequired to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles.
    • Sequence similaritiesBelongs to the FNBP1 family.
      Contains 1 FCH domain.
      Contains 1 REM (Hr1) repeat.
      Contains 1 SH3 domain.
    • Cellular localizationCytoplasm. Cytoplasm > cytoskeleton. Cytoplasm > cell cortex. Cytoplasmic vesicle. Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • C1orf39 antibody
      • FBP1L_HUMAN antibody
      • FNBP 1L antibody
      • fnbp1l antibody
      • Formin binding protein 1 like antibody
      • Formin-binding protein 1-like antibody
      • TOCA 1 antibody
      • Toca-1 antibody
      • TOCA1 antibody
      • Transducer of Cdc42 dependent actin assembly 1 antibody
      • Transducer of Cdc42 dependent actin assembly protein 1 antibody
      • Transducer of Cdc42-dependent actin assembly protein 1 antibody
      see all

    Anti-FNBP1L antibody images

    • Lane 1: Staining of FNBP1L in Jurkat whole cell lysate immunoprecipitated using ab124277 at 6 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Lane 2: control IgG.
      Predicted band size : 70 kDa. Exposure time: 30 seconds

    References for Anti-FNBP1L antibody (ab124277)

    ab124277 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab124277.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"