Overview

  • Product nameAnti-FNBP1L antibody
    See all FNBP1L primary antibodies
  • Description
    Rabbit polyclonal to FNBP1L
  • Tested applicationsSuitable for: ICC/IF, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A 15 amino acid synthetic peptide from near the amino terminus of human FNBP1L.

  • Positive control
    • Human brain tissue lysate. Human brain tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab67311 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 70 kDa).
IHC-P Use a concentration of 2.5 µg/ml.

Target

  • FunctionRequired to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles.
  • Sequence similaritiesBelongs to the FNBP1 family.
    Contains 1 FCH domain.
    Contains 1 REM (Hr1) repeat.
    Contains 1 SH3 domain.
  • Cellular localizationCytoplasm. Cytoplasm > cytoskeleton. Cytoplasm > cell cortex. Cytoplasmic vesicle. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C1orf39 antibody
    • FBP1L_HUMAN antibody
    • FNBP 1L antibody
    • fnbp1l antibody
    • Formin binding protein 1 like antibody
    • Formin-binding protein 1-like antibody
    • TOCA 1 antibody
    • Toca-1 antibody
    • TOCA1 antibody
    • Transducer of Cdc42 dependent actin assembly 1 antibody
    • Transducer of Cdc42 dependent actin assembly protein 1 antibody
    • Transducer of Cdc42-dependent actin assembly protein 1 antibody
    see all

Anti-FNBP1L antibody images

  • All lanes : Anti-FNBP1L antibody (ab67311) at 0.5 µg/ml

    Lane 1 : Human brain tissue lysate with no blocking peptide
    Lane 2 : Human brain tissue lysate with blocking peptide

    Lysates/proteins at 15 µg/ml per lane.


    Predicted band size : 70 kDa
    Observed band size : 70 kDa
  • ab67311 at 2.5μg/ml  staining of FNBP1L in human brain tissue using IHC-P.
  • Immunofluorescence of TOCA-1 in Human Brain cells using ab67311 at 20 ug/ml.

References for Anti-FNBP1L antibody (ab67311)

ab67311 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"