This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

Overview

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris-saline. pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Fast track antibodies constitute a diverse group of products that have been released to accelerate your research, but are not yet fully characterized. They have all been affinity purified and show high titre values against the immunizing peptide (by ELISA). Fast track terms of use

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 110 kDa.Can be blocked with Human FNBP3 peptide (ab23236). Preliminary experiments gave an ~28kDa band in A549 lysates at 1ug/ml, this band was successfully blocked by incubation with the immunising peptide. Please note that currently we cannot find a definitive explanation in the literature for the band we observe given the predicted size of ~110kDda.

Target

  • Function
    Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). May be involved in pre-mRNA splicing.
  • Tissue specificity
    Expressed in the brain cortex (at protein level). Widely expressed.
  • Sequence similarities
    Belongs to the PRPF40 family.
    Contains 5 FF domains.
    Contains 2 WW domains.
  • Domain
    The WW domains are essential for localization to nuclear speckles.
  • Cellular localization
    Nucleus speckle. Nucleus matrix. Colocalizes with AKAP8L in the nuclear matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • Fas ligand associated factor 1 antibody
    • Fas ligand-associated factor 1 antibody
    • FBP 11 antibody
    • FBP11 antibody
    • FLAF 1 antibody
    • FLAF1 antibody
    • FNBP 3 antibody
    • Formin binding protein 11 antibody
    • Formin binding protein 3 antibody
    • Formin-binding protein 11 antibody
    • Formin-binding protein 3 antibody
    • HIP-10 antibody
    • HIP10 antibody
    • Huntingtin interacting protein A antibody
    • Huntingtin interacting protein HYPA antibody
    • Huntingtin yeast partner A antibody
    • Huntingtin-interacting protein 10 antibody
    • Huntingtin-interacting protein A antibody
    • HYPA antibody
    • NY REN 6 antibody
    • NY REN 6 antigen antibody
    • PR40A_HUMAN antibody
    • Pre mRNA processing factor 40 homolog A antibody
    • Pre-mRNA-processing factor 40 homolog A antibody
    • PRP40 pre mRNA processing factor 40 homolog A (S cerevisiae) antibody
    • PRP40 pre mRNA processing factor 40 homolog A (yeast) antibody
    • PRP40 pre mRNA processing factor 40 homolog A antibody
    • PRPF 40A antibody
    • PRPF40A antibody
    • Renal carcinoma antigen NY-REN-6 antibody
    see all

References for Anti-FNBP3 antibody (ab13774)

ab13774 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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