Overview

  • Product nameAnti-FNIP2 antibody
    See all FNIP2 primary antibodies
  • Description
    Rabbit polyclonal to FNIP2
  • SpecificityMultiple isoforms of FNIP2 are known to exist. This antibody is predicted not to cross-react with FNIP1.
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    An 18 amino acid peptide near the N terminus of Human FNIP2 (NP_065891).

  • Positive control
    • Mouse skeletal muscle lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab106605 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 122 kDa.

Target

  • FunctionMay play a role in the signal transduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions (By similarity). May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1.
  • Tissue specificityWidely expressed with highest levels in muscle, nasal mucosa, salivary gland, uvula, fat, liver, heart, placenty and pancreas. Moderately expressed in the lung, small intestine, kidney and brain. Lower levels detected in renal cell carcinoma than in normal kidney tissue. Higher levels detected in oncocytoma than in normal kidney.
  • Sequence similaritiesBelongs to the FNIP family.
  • Post-translational
    modifications
    Phosphorylated by AMPK.
  • Cellular localizationCytoplasm. Co-localizes with FLCN in the cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • FNIP1-like protein antibody
    • Fnip2 antibody
    • FNIP2_HUMAN antibody
    • FNIPL antibody
    • Folliculin-interacting protein 2 antibody
    • KIAA1450 antibody
    • MAPO1 antibody
    • O6-methylguanine-induced apoptosis 1 protein antibody
    • OTTHUMP00000221326 antibody
    see all

Anti-FNIP2 antibody images

  • Lane 1 : Anti-FNIP2 antibody (ab106605) at 1 µg/ml
    Lane 2 : Anti-FNIP2 antibody (ab106605) at 2 µg/ml

    Lane 1 : Mouse skeletal muscle lysate
    Lane 2 : Mouse skeletal muscle lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 122 kDa

References for Anti-FNIP2 antibody (ab106605)

ab106605 has not yet been referenced specifically in any publications.

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