Overview

  • Product nameAnti-FNIP2 antibody
    See all FNIP2 primary antibodies
  • Description
    Rabbit polyclonal to FNIP2
  • Specificityab106611 is predicted to not cross-react with FNIP1.
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to 16 amino acids near the C terminal end of Human FNIP2 (NP_065891).

  • Positive control
    • Rat skeletal muscle lysate Mouse skeletal muscle tissue

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab106611 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 122 kDa.

Target

  • FunctionMay play a role in the signal transduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions (By similarity). May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1.
  • Tissue specificityWidely expressed with highest levels in muscle, nasal mucosa, salivary gland, uvula, fat, liver, heart, placenty and pancreas. Moderately expressed in the lung, small intestine, kidney and brain. Lower levels detected in renal cell carcinoma than in normal kidney tissue. Higher levels detected in oncocytoma than in normal kidney.
  • Sequence similaritiesBelongs to the FNIP family.
  • Post-translational
    modifications
    Phosphorylated by AMPK.
  • Cellular localizationCytoplasm. Co-localizes with FLCN in the cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • FNIP1-like protein antibody
    • Fnip2 antibody
    • FNIP2_HUMAN antibody
    • FNIPL antibody
    • Folliculin-interacting protein 2 antibody
    • KIAA1450 antibody
    • MAPO1 antibody
    • O6-methylguanine-induced apoptosis 1 protein antibody
    • OTTHUMP00000221326 antibody
    see all

Anti-FNIP2 antibody images

  • Lane 1 : Anti-FNIP2 antibody (ab106611) at 1 µg/ml
    Lane 2 : Anti-FNIP2 antibody (ab106611) at 2 µg/ml

    Lane 1 : Rat skeletal muscle lysate
    Lane 2 : Rat skeletal muscle lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 122 kDa
  • ab106611, at 5µg/ml, staining FNIP2 in paraffin embedded Mouse skeletal muscle tissue by Immunohistochemistry.

References for Anti-FNIP2 antibody (ab106611)

ab106611 has not yet been referenced specifically in any publications.

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