Overview

  • Product name
  • Description
    Rabbit polyclonal to FNTA
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Chicken, Dog, Human, Chimpanzee
  • Immunogen

    Synthetic peptide, corresponding to a portion of the amino acids 150-250 of Human FNTA

  • Positive control
    • Human prostate tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab77984 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 44 kDa.
IHC-P Use a concentration of 10 µg/ml.

Target

  • Function
    Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate. Through RAC1 prenylation and activation may positively regulate neuromuscular junction development downstream of MUSK.
  • Sequence similarities
    Belongs to the protein prenyltransferase subunit alpha family.
    Contains 5 PFTA repeats.
  • Post-translational
    modifications
    Phosphorylated. Phosphorylation is mediated by MUSK upon AGRIN stimulation and results in the activation of FNTA.
  • Information by UniProt
  • Database links
  • Alternative names
    • CAAX farnesyltransferase alpha subunit antibody
    • CAAX farnesyltransferase subunit alpha antibody
    • EC 2.5.1.58 antibody
    • EC 2.5.1.59 antibody
    • Farnesyl protein transferase alpha subunit antibody
    • Farnesyltransferase CAAX box alpha antibody
    • Farnesyltransferase, CAAX box, alpha antibody
    • Fnta antibody
    • FNTA_HUMAN antibody
    • FPTA antibody
    • FTase alpha antibody
    • FTase-alpha antibody
    • GGTase I alpha antibody
    • GGTase-I-alpha antibody
    • MGC99680 antibody
    • OTTHUMP00000229206 antibody
    • OTTHUMP00000229262 antibody
    • PGGT1A antibody
    • Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit antibody
    • Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha antibody
    • Protein prenyltransferase alpha subunit repeat containing 2 antibody
    • PTAR2 antibody
    • Ras proteins prenyltransferase alpha antibody
    • Ras proteins prenyltransferase subunit alpha antibody
    • Type I protein geranyl geranyltransferase alpha subunit antibody
    • Type I protein geranyl-geranyltransferase subunit alpha antibody
    see all

Images

  • ab77984 at 10µg/ml staining FNTA in human prostate tissue by Immunohistochemistry using formalin-fixed, paraffin-embedded tissue.

References

ab77984 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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