Overview

  • Product nameAnti-FNTA antibody
    See all FNTA primary antibodies
  • Description
    Rabbit polyclonal to FNTA
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 1-50 (MAATEGVGEA AQGGEPGQPA QPPPQPHPPP PQQQHKEEMA AEAGEAVASP) of Human FNTA (NP_001018197)

  • Positive control
    • THP-1 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab98042 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 36 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionCatalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate. Through RAC1 prenylation and activation may positively regulate neuromuscular junction development downstream of MUSK.
  • Sequence similaritiesBelongs to the protein prenyltransferase subunit alpha family.
    Contains 5 PFTA repeats.
  • Post-translational
    modifications
    Phosphorylated. Phosphorylation is mediated by MUSK upon AGRIN stimulation and results in the activation of FNTA.
  • Information by UniProt
  • Database links
  • Alternative names
    • CAAX farnesyltransferase alpha subunit antibody
    • CAAX farnesyltransferase subunit alpha antibody
    • EC 2.5.1.58 antibody
    • EC 2.5.1.59 antibody
    • Farnesyl protein transferase alpha subunit antibody
    • Farnesyltransferase CAAX box alpha antibody
    • Farnesyltransferase, CAAX box, alpha antibody
    • Fnta antibody
    • FNTA_HUMAN antibody
    • FPTA antibody
    • FTase alpha antibody
    • FTase-alpha antibody
    • GGTase I alpha antibody
    • GGTase-I-alpha antibody
    • MGC99680 antibody
    • OTTHUMP00000229206 antibody
    • OTTHUMP00000229262 antibody
    • PGGT1A antibody
    • Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit antibody
    • Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha antibody
    • Protein prenyltransferase alpha subunit repeat containing 2 antibody
    • PTAR2 antibody
    • Ras proteins prenyltransferase alpha antibody
    • Ras proteins prenyltransferase subunit alpha antibody
    • Type I protein geranyl geranyltransferase alpha subunit antibody
    • Type I protein geranyl-geranyltransferase subunit alpha antibody
    see all

Anti-FNTA antibody images

  • Anti-FNTA antibody (ab98042) at 1 µg/ml + THP-1 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 36 kDa

References for Anti-FNTA antibody (ab98042)

ab98042 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab98042.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"