The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent concentration. PubMed: 23439585ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
Use at an assay dependent concentration. Predicted molecular weight: 29 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
Use at an assay dependent concentration.
FunctionBinds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells.
Tissue specificityExpressed in placenta and hematopoietic cells. Expression is increased in malignant tissues.
Sequence similaritiesBelongs to the folate receptor family.
Post-translational modificationsEight disulfide bonds are present. N-glycosylated.
Perna AF et al. Altered folate receptor 2 expression in uraemic patients on haemodialysis: implications for folate resistance. Nephrol Dial TransplantN/A:N/A (2013).
WB, Flow Cyt
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Stronach EA et al. HDAC4-regulated STAT1 activation mediates platinum resistance in ovarian cancer. Cancer Res71:4412-22 (2011).
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