Overview

  • Product nameAnti-FOLR2 antibody
    See all FOLR2 primary antibodies
  • Description
    Rabbit polyclonal to FOLR2
  • Tested applicationsSuitable for: Flow Cyt, WB, ELISAmore details
  • Species reactivity
    Reacts with: Human, Recombinant Fragment
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to N terminal residues of human FOLR2

Properties

Applications

Our Abpromise guarantee covers the use of ab56067 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration. PubMed: 23439585ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
WB Use at an assay dependent concentration. Predicted molecular weight: 29 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA Use at an assay dependent concentration.

Target

  • FunctionBinds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells.
  • Tissue specificityExpressed in placenta and hematopoietic cells. Expression is increased in malignant tissues.
  • Sequence similaritiesBelongs to the folate receptor family.
  • Post-translational
    modifications
    Eight disulfide bonds are present.
    N-glycosylated.
  • Cellular localizationCell membrane. Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • beta hFR antibody
    • FBP antibody
    • FBP/PL 1 antibody
    • FBP2 antibody
    • fetal/placental antibody
    • folate receptor 2 (fetal) antibody
    • Folate receptor 2 antibody
    • Folate receptor antibody
    • Folate receptor beta antibody
    • Folate receptor, fetal/placental antibody
    • Folbp 2 antibody
    • Folbp2 antibody
    • Folr2 antibody
    • FOLR2_HUMAN antibody
    • FR beta antibody
    • FR P3 antibody
    • FR-beta antibody
    • Placental folate binding protein antibody
    • Placental folate-binding protein antibody
    see all

References for Anti-FOLR2 antibody (ab56067)

This product has been referenced in:
  • Perna AF  et al. Altered folate receptor 2 expression in uraemic patients on haemodialysis: implications for folate resistance. Nephrol Dial Transplant N/A:N/A (2013). WB, Flow Cyt ; Human . Read more (PubMed: 23439585) »
  • Stronach EA  et al. HDAC4-regulated STAT1 activation mediates platinum resistance in ovarian cancer. Cancer Res 71:4412-22 (2011). WB ; Human . Read more (PubMed: 21571862) »

See all 2 Publications for this product

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Sample Human Cell (THP-1)
Specification THP-1
Fixative Paraformaldehyde
Permeabilization No
Blocking step Protein Block (serum free) as blocking agent for 20 minute(s) · Concentration: 100% · Temperature: 4°C
Username

Mr. Alan Maziarz

Verified customer

Submitted Oct 14 2008

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"