The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent dilution. Detection limit for recombinant tagged Human FOLR2 fragment is approximately 1ng/ml when used as a capture antibody.
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 29 kDa. This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
FunctionBinds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells.
Tissue specificityExpressed in placenta and hematopoietic cells. Expression is increased in malignant tissues.
Sequence similaritiesBelongs to the folate receptor family.
Post-translational modificationsEight disulfide bonds are present. N-glycosylated.